SCHEMBL15629451

SCHEMBL15629451

CN=Nc1c(S(=O)(=O)O)cc2cc(Nc3ccccc3)ccc2c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 2/20 0.58
PRMT3 O60678 1/20 0.58
EP300 Q09472 1/20 0.58
PRMT6 Q96LA8 1/20 0.58
ENPP2 Q13822 8/20 0.56
PHLPP2 Q6ZVD8 2/20 0.56
TNNI3 P19429 1/20 0.51
TNNT2 P45379 1/20 0.51
TNNC1 P63316 1/20 0.51
HKDC1 Q2TB90 1/20 0.51
NSD2 O96028 1/20 0.50
DUSP3 P51452 1/20 0.50
PTPN5 P54829 1/20 0.50
CASP7 P55210 1/20 0.50
CASP6 P55212 1/20 0.50
PTPN11 Q06124 1/20 0.50
SNCA P37840 1/20 0.47
CD40 P25942 1/20 0.47
CD40LG P29965 1/20 0.47
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17540329 0.93 PRMT1 (0.64) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL19235007 0.89 PRMT1 (0.52) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL17515769 0.88 PRMT1 (0.69) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL17540343 0.88 PRMT1 (0.69) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL19234785 0.87 ENPP2 (0.71) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL19235016 0.86 PRMT1 (0.57) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL19882710 0.86 ENPP2 (0.66) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL15629450 0.86 TNNI3 (0.53) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL15628292 0.85 PRMT1 (0.53) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL17545808 0.85 ENPP2 (0.69) PRMT1PRMT3EP300PRMT6ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10209418-B2 Achromatic polarization element, and polarization plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-02-19 US disclosed
US-20140087201-A1 Dye-Based Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-03-27 US disclosed