SCHEMBL17540329

SCHEMBL17540329

CN=Nc1ccc(N=Nc2ccc(N=Nc3c(S(=O)(=O)O)cc4cc(Nc5ccccc5)ccc4c3O)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 2/20 0.64
PRMT3 O60678 1/20 0.64
EP300 Q09472 1/20 0.64
PRMT6 Q96LA8 1/20 0.64
PHLPP2 Q6ZVD8 2/20 0.62
ENPP2 Q13822 9/20 0.60
CD40 P25942 1/20 0.53
CD40LG P29965 1/20 0.53
TNNI3 P19429 1/20 0.47
TNNT2 P45379 1/20 0.47
TNNC1 P63316 1/20 0.47
HKDC1 Q2TB90 1/20 0.47
CARM1 Q86X55 1/20 0.47
NSD2 O96028 1/20 0.46
DUSP3 P51452 1/20 0.46
PTPN5 P54829 1/20 0.46
CASP7 P55210 1/20 0.46
CASP6 P55212 1/20 0.46
PTPN11 Q06124 1/20 0.46
CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17515769 0.93 PRMT1 (0.69) PRMT1PRMT3EP300PRMT6PHLPP2
SCHEMBL15629451 0.93 PRMT1 (0.58) PRMT1PRMT3EP300PRMT6PHLPP2
SCHEMBL17540343 0.93 PRMT1 (0.69) PRMT1PRMT3EP300PRMT6PHLPP2
SCHEMBL19235016 0.91 PRMT1 (0.57) PRMT1PRMT3EP300PRMT6PHLPP2
SCHEMBL12757456 0.90 ENPP2 (0.69) PRMT1PRMT3EP300PRMT6PHLPP2
SCHEMBL13350540 0.90 ENPP2 (0.69) PRMT1PRMT3EP300PRMT6PHLPP2
SCHEMBL17545808 0.90 ENPP2 (0.69) PRMT1PRMT3EP300PRMT6PHLPP2
SCHEMBL29538227 0.90 ENPP2 (0.71) PRMT1PRMT3EP300PRMT6PHLPP2
SCHEMBL20747587 0.89 PRMT1 (0.62) PRMT1PRMT3EP300PRMT6PHLPP2
SCHEMBL17515775 0.88 PRMT3 (0.61) PRMT1PRMT3EP300PRMT6PHLPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170153361-A1 Achromatic Polarizing Plate With High-Transmissivity And High-Degree Of Polarization NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-06-01 US disclosed
US-20160041322-A1 Achromatic Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 US disclosed