Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 12/20 | 0.67 |
| ▸ | PNP | P00491 | 3/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | POLG | P54098 | 1/20 | 0.54 |
| ▸ | TK1 | P04183 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | VCP | P55072 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15630219 | 0.92 | PNP (0.64) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL15630250 | 0.91 | POLG (0.65) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL571368 | 0.91 | POLG (0.65) | HPRT1PNPBLMUSP2TSHR | |
| Omaciclovir SCHEMBL571367 | 0.87 | HPRT1 (0.66) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL10506595 | 0.87 | TK1 (0.65) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL16491196 | 0.86 | BLM (0.61) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL7196190 | 0.86 | HPRT1 (0.58) | HPRT1PNPBLMPOLGTK1 | |
| SCHEMBL15630233 | 0.86 | HPRT1 (0.64) | HPRT1PNPBLMUSP2TSHR | |
| SCHEMBL24941684 | 0.85 | HPRT1 (0.77) | HPRT1PNPPOLG | |
| Ammonia Solution, Strong SCHEMBL5930250 | 0.85 | HPRT1 (0.57) | HPRT1PNPBLMPOLGTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014047562-A2 | METHOD OF TREATING AND/OR PREVENTING SHINGLES AND METHOD OF TREATING AND/OR PREVENTING ZOSTER ASSOCIATED PAIN | EPIPHANY BIOSCIENCES (US) | 2014-03-27 | — | — | WO | disclosed |