Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21800978 | 0.86 | CYP2C19 (0.58) | ITGB3ITGB1ITGAVITGA5POLB | |
| SCHEMBL12949884 | 0.80 | POLB (0.50) | AGERPOLBRAB9ANPC1KDM4E | |
| SCHEMBL9848863 | 0.79 | NPC1 (0.62) | POLBCYP2C19RAB9ANPC1KDM4E | |
| SCHEMBL436270 | 0.77 | KEAP1 (0.49) | POLBRAB9AKEAP1HPGDGAA | |
| SCHEMBL15630971 | 0.77 | KEAP1 (0.49) | POLBRAB9ANPC1KDM4EHSD17B10 | |
| SCHEMBL15610699 | 0.75 | NPC1 (0.44) | AGERITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL15630439 | 0.75 | SMN1; SMN2 (0.46) | AGERRAB9ANPC1KDM4EKEAP1 | |
| SCHEMBL15630981 | 0.75 | SMN1; SMN2 (0.46) | AGERRAB9ANPC1KDM4EKEAP1 | |
| SCHEMBL14817806 | 0.75 | ALDH1A1 (0.65) | POLBCYP2C19RAB9ANPC1KDM4E | |
| SCHEMBL436284 | 0.75 | KEAP1 (0.57) | RAB9AKEAP1ALDH1A1LMNAEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906344-B2 | F-18 radiolabeled compounds for diagnosing and monitoring kidney function | KASINA LAILA INNOVA PHARMACEUTICALS PRIVATE LIMITED (IN) | 2014-12-09 | — | — | US | disclosed |
| US-20140086837-A1 | F-18 RADIOLABELED COMPOUNDS FOR DIAGNOSING AND MONITORING KIDNEY FUNCTION | KASINA LAILA INNOVA PHARMACEUTICALS PRIVATE LIMITED (IN) | 2014-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140086837-A1 | F-18 RADIOLABELED COMPOUNDS FOR DIAGNOSING AND MONITORING KIDNEY FUNCTION | SLCO1B1, SLCO1B3, SLCO2B1 | AGER 1136/4885ITGB3 3335/4885ITGB1 3422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.