Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.73 |
| ▸ | IKBKB | O14920 | 1/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
| ▸ | ESRRG | P62508 | 1/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.65 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563547 | 1.00 | DNM1 (0.73) | DNM1IKBKBESR1ESRRGESR2 | |
| SCHEMBL6636776 | 1.00 | DNM1 (0.73) | DNM1IKBKBESR1ESRRGESR2 | |
| SCHEMBL8769045 | 0.93 | DNM1 (0.76) | DNM1IKBKBESR1ESRRGESR2 | |
| SCHEMBL1563601 | 0.90 | ESRRG (0.85) | DNM1IKBKBESR1ESRRGESR2 | |
| SCHEMBL6634693 | 0.90 | ESRRG (0.85) | DNM1IKBKBESR1ESRRGESR2 | |
| SCHEMBL1563599 | 0.90 | ESRRG (0.85) | DNM1IKBKBESR1ESRRGESR2 | |
| SCHEMBL1563731 | 0.86 | DNM1 (0.67) | DNM1IKBKBESR1ESRRGESR2 | |
| SCHEMBL6635676 | 0.86 | DNM1 (0.67) | DNM1IKBKBESR1ESRRGESR2 | |
| SCHEMBL1563733 | 0.86 | DNM1 (0.67) | DNM1IKBKBESR1ESRRGESR2 | |
| SCHEMBL13569020 | 0.86 | ESR1 (0.89) | DNM1IKBKBESR1ESRRGESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130344165-A1 | JAB1 INHIBITORY COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2013-12-26 | — | — | US | claimed |
| WO-2012116137-A2 | JAB1 BLOCKING COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2012-08-30 | — | — | WO | claimed |
| US-12377194-B2 | JAB1 inhibitory compositions for ossification and methods related thereto | EMORY UNIVERSITY (US) | 2025-08-05 | — | — | US | disclosed |
| US-20220023506-A1 | JAB1 Inhibitory Compositions for Ossification and Methods Related Thereto | EMORY UNIVERSITY | 2022-01-27 | — | — | US | disclosed |
| US-11179500-B2 | JAB1 inhibitory compositions for ossification and methods related thereto | EMORY UNIVERSITY (US) | 2021-11-23 | — | — | US | disclosed |
| US-9556351-B2 | Rubber composition suitable for use as a cap ply in a tire | Bridgestone Americas Tire Operations, Inc. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20160040024-A1 | RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC | 2016-02-11 | — | — | US | disclosed |
| US-9163127-B2 | Rubber composition suitable for use as a cap ply in a tire | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140005320-A1 | RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2014-01-02 | — | — | US | disclosed |
| US-20130344165-A1 | JAB1 INHIBITORY COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2013-12-26 | — | — | US | disclosed |
| EP-2665771-A2 | A RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE | Bridgestone Americas Tire Operations, LLC (US) | 2013-11-27 | — | — | EP | disclosed |
| US-6822027-B2 | MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. | BRIDGESTONE CORPORATION (JP) | 2004-11-23 | — | — | US | disclosed |
| EP-1475408-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM | Bridgestone Corporation (JP) | 2004-11-10 | — | — | EP | disclosed |
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6506849-B1 | Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity | BRIDGESTONE CORPORATION (JP) | 2003-01-14 | — | — | US | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| US-20020049294-A1 | Rubber composition and heavy duty pneumatic tire using the rubber composition | BRIDGESTONE CORPORATION | 2002-04-25 | — | — | US | disclosed |
| EP-1184412-A1 | Rubber composition and heavy duty pneumetic tire using the rubber composition | Bridgestone Corporation (JP) | 2002-03-06 | — | — | EP | disclosed |
| EP-1083199-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2001-03-14 | — | — | EP | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |