SCHEMBL1563733

SCHEMBL1563733

COc1ccc(C=NNC(=O)c2ccc3ccccc3c2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DNM1 Q05193 1/20 0.67
▸ MAPT P10636 6/20 0.67
▸ KMT2A Q03164 4/20 0.67
▸ MEN1 O00255 3/20 0.67
▸ IKBKB O14920 1/20 0.67
▸ KDM4E B2RXH2 4/20 0.64
▸ POLB P06746 1/20 0.64
▸ ESR1 P03372 1/20 0.63
▸ ESRRG P62508 1/20 0.63
▸ ESR2 Q92731 1/20 0.63
▸ HPGD P15428 3/20 0.61
▸ ALDH1A1 P00352 3/20 0.61
▸ HTT P42858 1/20 0.61
▸ SMN1; SMN2 Q16637 1/20 0.61
▸ MGAM O43451 2/20 0.60
▸ GAA P10253 1/20 0.60
▸ SI P14410 1/20 0.60
▸ MGAM2 Q2M2H8 1/20 0.60
▸ NPC1 O15118 2/20 0.60
▸ CASP3 P42574 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1563731 1.00 DNM1 (0.67) DNM1MAPTKMT2AMEN1IKBKB
SCHEMBL6635676 1.00 DNM1 (0.67) DNM1MAPTKMT2AMEN1IKBKB
SCHEMBL28453782 0.88 SIRT1 (0.63) MAPTKMT2AMEN1KDM4EPOLB
SCHEMBL1563549 0.86 DNM1 (0.73) DNM1MAPTKMT2AMEN1IKBKB
SCHEMBL1563547 0.86 DNM1 (0.73) DNM1MAPTKMT2AMEN1IKBKB
SCHEMBL6636776 0.86 DNM1 (0.73) DNM1MAPTKMT2AMEN1IKBKB
SCHEMBL12735427 0.86 MAPT (0.82) MAPTKMT2AMEN1KDM4EPOLB
SCHEMBL6634693 0.85 ESRRG (0.85) DNM1MAPTKMT2AMEN1IKBKB
SCHEMBL1563599 0.85 ESRRG (0.85) DNM1MAPTKMT2AMEN1IKBKB
SCHEMBL1563601 0.85 ESRRG (0.85) DNM1MAPTKMT2AMEN1IKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9556351-B2 Rubber composition suitable for use as a cap ply in a tire Bridgestone Americas Tire Operations, Inc. (US) 2017-01-31 — — US disclosed
US-20160040024-A1 RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2016-02-11 — — US disclosed
US-9163127-B2 Rubber composition suitable for use as a cap ply in a tire BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2015-10-20 — — US disclosed
US-20140005320-A1 RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2014-01-02 — — US disclosed
EP-2665771-A2 A RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE Bridgestone Americas Tire Operations, LLC (US) 2013-11-27 — — EP disclosed
WO-2012099955-A2 A RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2012-07-26 — — WO disclosed
EP-1475408-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM BRIDGESTONE CORP (JP) 2011-04-06 — — EP disclosed
EP-1083199-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2006-08-02 — — EP disclosed
US-20050176858-A1 Rubber composition and pneumatic tire made therefrom BRIDGESTONE CORPORATION 2005-08-11 — — US disclosed
EP-1184412-B1 Rubber composition and heavy duty pneumetic tire using the rubber composition BRIDGESTONE CORP (JP) 2005-01-12 — — EP disclosed
EP-0909788-B1 RUBBER COMPOSITION AND PNEUMATIC TIRES BRIDGESTONE CORP (JP) 2004-12-01 — — EP disclosed
US-6822027-B2 MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. BRIDGESTONE CORPORATION (JP) 2004-11-23 — — US disclosed
EP-1475408-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM Bridgestone Corporation (JP) 2004-11-10 — — EP disclosed
EP-1420044-A2 Rubber composition and pneumatic tire Bridgestone Corporation (JP) 2004-05-19 — — EP disclosed
US-6506849-B1 Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity BRIDGESTONE CORPORATION (JP) 2003-01-14 — — US disclosed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 — — US disclosed
US-20020049294-A1 Rubber composition and heavy duty pneumatic tire using the rubber composition BRIDGESTONE CORPORATION 2002-04-25 — — US disclosed
EP-1184412-A1 Rubber composition and heavy duty pneumetic tire using the rubber composition Bridgestone Corporation (JP) 2002-03-06 — — EP disclosed
EP-1083199-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2001-03-14 — — EP disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 — — EP disclosed
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