SCHEMBL1563601

SCHEMBL1563601

O=C(NN=Cc1ccc(O)cc1)c1ccc2ccccc2c1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESRRG P62508 4/20 0.85
▸ ESR1 P03372 1/20 0.85
▸ ESR2 Q92731 1/20 0.85
▸ DNM1 Q05193 1/20 0.76
▸ IKBKB O14920 1/20 0.71
▸ MAPT P10636 4/20 0.62
▸ RAB9A P51151 4/20 0.62
▸ GAA P10253 2/20 0.62
▸ NPC1 O15118 2/20 0.62
▸ ALDH1A1 P00352 2/20 0.62
▸ MCL1 Q07820 1/20 0.62
▸ TDP1 Q9NUW8 1/20 0.62
▸ KMT2A Q03164 4/20 0.60
▸ MEN1 O00255 3/20 0.60
▸ SIRT1 Q96EB6 1/20 0.60
▸ MGAM O43451 1/20 0.60
▸ SI P14410 1/20 0.60
▸ MGAM2 Q2M2H8 1/20 0.60
▸ L3MBTL1 Q9Y468 1/20 0.60
▸ LMNA P02545 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6634693 1.00 ESRRG (0.85) ESRRGESR1ESR2DNM1IKBKB
SCHEMBL1563599 1.00 ESRRG (0.85) ESRRGESR1ESR2DNM1IKBKB
SCHEMBL12937827 0.92 ESRRG (1.00) ESRRGESR1ESR2DNM1IKBKB
SCHEMBL1563549 0.90 DNM1 (0.73) ESRRGESR1ESR2DNM1IKBKB
SCHEMBL1563547 0.90 DNM1 (0.73) ESRRGESR1ESR2DNM1IKBKB
SCHEMBL6636776 0.90 DNM1 (0.73) ESRRGESR1ESR2DNM1IKBKB
SCHEMBL8769045 0.86 DNM1 (0.76) ESRRGESR1ESR2DNM1IKBKB
SCHEMBL13569020 0.85 ESR1 (0.89) ESRRGESR1ESR2DNM1IKBKB
SCHEMBL1563733 0.85 DNM1 (0.67) ESRRGESR1ESR2DNM1IKBKB
SCHEMBL6635676 0.85 DNM1 (0.67) ESRRGESR1ESR2DNM1IKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9556351-B2 Rubber composition suitable for use as a cap ply in a tire Bridgestone Americas Tire Operations, Inc. (US) 2017-01-31 — — US disclosed
US-20160040024-A1 RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2016-02-11 — — US disclosed
US-9163127-B2 Rubber composition suitable for use as a cap ply in a tire BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2015-10-20 — — US disclosed
US-20140005320-A1 RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2014-01-02 — — US disclosed
EP-2665771-A2 A RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE Bridgestone Americas Tire Operations, LLC (US) 2013-11-27 — — EP disclosed
WO-2012099955-A2 A RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2012-07-26 — — WO disclosed
EP-1475408-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM BRIDGESTONE CORP (JP) 2011-04-06 — — EP disclosed
US-20050176858-A1 Rubber composition and pneumatic tire made therefrom BRIDGESTONE CORPORATION 2005-08-11 — — US disclosed
EP-1184412-B1 Rubber composition and heavy duty pneumetic tire using the rubber composition BRIDGESTONE CORP (JP) 2005-01-12 — — EP disclosed
EP-0909788-B1 RUBBER COMPOSITION AND PNEUMATIC TIRES BRIDGESTONE CORP (JP) 2004-12-01 — — EP disclosed
US-6822027-B2 MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. BRIDGESTONE CORPORATION (JP) 2004-11-23 — — US disclosed
EP-1475408-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM Bridgestone Corporation (JP) 2004-11-10 — — EP disclosed
EP-1420044-A2 Rubber composition and pneumatic tire Bridgestone Corporation (JP) 2004-05-19 — — EP disclosed
US-6506849-B1 Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity BRIDGESTONE CORPORATION (JP) 2003-01-14 — — US disclosed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 — — US disclosed
US-20020049294-A1 Rubber composition and heavy duty pneumatic tire using the rubber composition BRIDGESTONE CORPORATION 2002-04-25 — — US disclosed
EP-1184412-A1 Rubber composition and heavy duty pneumetic tire using the rubber composition Bridgestone Corporation (JP) 2002-03-06 — — EP disclosed
EP-1083199-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2001-03-14 — — EP disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 — — EP disclosed
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