SCHEMBL15645814

SCHEMBL15645814

CC(C)(C)OC(=O)C1C2C=CC(C(C(=O)O)C2C(=O)O)C1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.43
TDP1 Q9NUW8 3/20 0.43
CTDSP1 Q9GZU7 1/20 0.38
MAPK1 P28482 1/20 0.35
APEX1 P27695 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
BTK Q06187 1/20 0.31
RECQL P46063 1/20 0.31
GPR119 Q8TDV5 1/20 0.30
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15645762 0.78 POLB (0.48) POLBTDP1CTDSP1APEX1
SCHEMBL5494856 0.78 POLB (0.48) POLBTDP1CTDSP1APEX1
SCHEMBL15645293 0.78 POLB (0.48) POLBTDP1CTDSP1APEX1
SCHEMBL15645760 0.78 POLB (0.48) POLBTDP1CTDSP1APEX1
SCHEMBL31453818 0.78 POLB (0.50) POLBTDP1CTDSP1APEX1
SCHEMBL2511575 0.78 POLB (0.50) POLBTDP1CTDSP1APEX1
SCHEMBL3150000 0.77 POLB (0.51) POLBTDP1APEX1
SCHEMBL5837416 0.77 POLB (0.51) POLBTDP1APEX1
SCHEMBL106105 0.76 POLB (0.65) POLBTDP1CTDSP1APEX1NFKB1
SCHEMBL16213867 0.75 HRH3 (0.38) MAPK1HRH3BTKGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2725067-B1 FLAMEPROOFED ALICYCLIC POLYIMIDE RESIN COMPOSITION AND THIN-WALLED MOLDED BODY OF SAME MITSUBISHI GAS CHEMICAL CO (JP) 2016-02-24 EP disclosed
EP-2725067-A1 FLAMEPROOFED ALICYCLIC POLYIMIDE RESIN COMPOSITION AND THIN-WALLED MOLDED BODY OF SAME Mitsubishi Gas Chemical Company, Inc. (JP) 2014-04-30 EP disclosed
US-20140114000-A1 FLAMEPROOFED ALICYCLIC POLYIMIDE RESIN COMPOSITION AND THIN-WALLED MOLDED BODY OF SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-04-24 US disclosed