Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15665400 | 0.82 | GAA (0.43) | GAAKDM4EMAPTPKMMEN1 | |
| SCHEMBL15665495 | 0.81 | MAOA (0.53) | NOS1CYP2D6NOS3NOS2LMNA | |
| SCHEMBL3245281 | 0.80 | RECQL (0.48) | GAAKDM4EMAPTRAB9ANOS1 | |
| SCHEMBL15665442 | 0.77 | MAOA (0.34) | GAAKDM4EMAPTNOS1CYP2D6 | |
| SCHEMBL27984535 | 0.76 | MEN1 (0.47) | GAAKDM4EMAPTPKMMEN1 | |
| SCHEMBL28667124 | 0.74 | CA2 (0.50) | GAAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL15664821 | 0.73 | MAOA (0.49) | NOS1CYP2D6NOS3NOS2LMNA | |
| SCHEMBL15665053 | 0.72 | MAOB (0.47) | NOS1CYP2D6NOS3NOS2LMNA | |
| SCHEMBL2777255 | 0.72 | TDP1 (0.48) | GAAKDM4EMAPTMEN1RAB9A | |
| SCHEMBL15665350 | 0.71 | MAOA (0.46) | NOS1ALDH1A1CYP19A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946325-B2 | Tire member and method for manufacturing the same | TOYO TIRE & RUBBER CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| US-20140128498-A1 | TIRE MEMBER AND METHOD FOR MANUFACTURING THE SAME | TOYO TIRE & RUBBER CO., LTD. (JP) | 2014-05-08 | — | — | US | disclosed |
| US-20140128525-A1 | TIRE MEMBER AND METHOD FOR MANUFACTURING THE SAME | TOYO TIRE & RUBBER CO., LTD. (JP) | 2014-05-08 | — | — | US | disclosed |