Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16056678 | 0.88 | DNM1 (0.41) | ZDHHC7OPRM1SMPD1PTPN1SPHK1 | |
| SCHEMBL14339562 | 0.82 | OPRM1 (0.41) | ZDHHC7OPRM1SMPD1PTPN1SPHK1 | |
| SCHEMBL14733283 | 0.78 | LMNA (0.49) | ZDHHC7FAAHLMNA | |
| SCHEMBL14733284 | 0.78 | LMNA (0.49) | ZDHHC7FAAHLMNA | |
| SCHEMBL13737406 | 0.77 | TSHR (0.53) | ZDHHC7FAAHSMPD1PTPN1ADH1B | |
| SCHEMBL1659278 | 0.77 | OPRM1 (0.41) | ZDHHC7OPRM1SMPD1PTPN1SPHK1 | |
| SCHEMBL27142176 | 0.77 | OPRM1 (0.37) | ZDHHC7OPRM1SMPD1PTPN1SPHK1 | |
| SCHEMBL6470973 | 0.77 | OPRM1 (0.37) | ZDHHC7OPRM1SMPD1PTPN1SPHK1 | |
| SCHEMBL1657370 | 0.77 | LMNA (0.48) | ZDHHC7OPRM1SMPD1PTPN1SPHK1 | |
| SCHEMBL13962830 | 0.76 | OPRM1 (0.42) | ZDHHC7FAAHCNR1CNR2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9945852-B2 | Method for determining the presence or absence of a biomarker | ARCIS BIOTECHNOLOGY HOLDINGS LIMITED (GB) | 2018-04-17 | — | — | US | disclosed |
| EP-2705367-B1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | BANGOR UNIV (GB) | 2017-04-26 | — | — | EP | disclosed |
| US-20140127709-A1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | BANGOR UNIVERSITY (GB) | 2014-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127709-A1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | CA14, CD63, CA12 | ZDHHC7 2947/4885FAAH 4244/4885CNR1 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.