Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22229862 | 1.00 | LTA4H (0.57) | LTA4HMMEOPRD1OPRM1OPRK1 | |
| SCHEMBL13878268 | 1.00 | LTA4H (0.57) | LTA4HMMEOPRD1OPRM1OPRK1 | |
| SCHEMBL30890866 | 0.92 | OPRD1 (0.60) | OPRD1OPRM1OPRK1 | |
| SCHEMBL4751778 | 0.91 | LTA4H (0.56) | LTA4HMMEOPRD1OPRM1OPRK1 | |
| SCHEMBL29692598 | 0.90 | OPRD1 (0.57) | OPRD1OPRM1OPRK1 | |
| SCHEMBL30051567 | 0.90 | MMP8 (0.56) | LTA4HMMEOPRD1OPRM1OPRK1 | |
| SCHEMBL28130929 | 0.89 | OPRD1 (0.56) | LTA4HOPRD1OPRM1OPRK1 | |
| SCHEMBL24235664 | 0.89 | LTA4H (0.62) | LTA4HMMEOPRD1 | |
| SCHEMBL29350735 | 0.88 | OPRD1 (0.58) | MMEOPRD1OPRM1OPRK1ACE | |
| SCHEMBL29569076 | 0.88 | MME (0.54) | MMEOPRD1OPRM1OPRK1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914600-A2 | FUNCTIONALIZED 9-BROMO-CAMPTOTHECIN DERIVATIVES | Nerviano Medical Sciences S.r.l. (IT) | 2015-09-09 | — | — | EP | claimed |
| WO-2014067960-A9 | FUNCTIONALIZED 9-BROMO-CAMPTOTHECIN DERIVATIVES | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-07-09 | — | — | WO | claimed |
| WO-2014067960-A2 | FUNCTIONALIZED 9-BROMO-CAMPTOTHECIN DERIVATIVES | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2014-05-08 | — | — | WO | claimed |
| EP-2914600-A2 | FUNCTIONALIZED 9-BROMO-CAMPTOTHECIN DERIVATIVES | Nerviano Medical Sciences S.r.l. (IT) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014067960-A9 | FUNCTIONALIZED 9-BROMO-CAMPTOTHECIN DERIVATIVES | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-07-09 | — | — | WO | disclosed |
| WO-2014067960-A2 | FUNCTIONALIZED 9-BROMO-CAMPTOTHECIN DERIVATIVES | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2014-05-08 | — | — | WO | disclosed |