SCHEMBL15670461

SCHEMBL15670461

COC[C@H](NCc1ccccc1)C(=O)NCc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.74
CA1 P00915 1/20 0.74
CA2 P00918 1/20 0.74
CA3 P07451 1/20 0.74
CA4 P22748 1/20 0.74
CA6 P23280 1/20 0.74
CA5A P35218 1/20 0.74
CA7 P43166 1/20 0.74
CACNA1C Q13936 1/20 0.74
SCN9A Q15858 1/20 0.74
CA9 Q16790 1/20 0.74
CA13 Q8N1Q1 1/20 0.74
CA14 Q9ULX7 1/20 0.74
CA5B Q9Y2D0 1/20 0.74
KMT2A Q03164 1/20 0.51
ATM Q13315 1/20 0.50
PKM P14618 1/20 0.49
MAPT P10636 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KCNT1 Q5JUK3 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15670460 1.00 CA12 (0.74) CA12CA1CA2CA3CA4
SCHEMBL8514186 1.00 CA12 (0.74) CA12CA1CA2CA3CA4
SCHEMBL2600863 0.88 CA12 (0.74) CA12CA1CA2CA3CA4
SCHEMBL527808 0.86 CA12 (0.81) CA12CA1CA2CA3CA4
SCHEMBL14931211 0.86 CA12 (0.81) CA12CA1CA2CA3CA4
Lacosamide SCHEMBL35330 0.85 CA12 (1.00) CA12CA1CA2CA3CA4
Lacosamide SCHEMBL223961 0.85 CA12 (1.00) CA12CA1CA2CA3CA4
Lacosamide SCHEMBL225889 0.85 CA12 (1.00) CA12CA1CA2CA3CA4
SCHEMBL15671411 0.84 CA12 (0.57) CA12CA1CA2CA3CA4
SCHEMBL224862 0.84 CA12 (0.57) CA12CA1CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2914574-B1 NEW PROCESS CAMBREX KARLSKOGA AB (SE) 2019-10-02 EP disclosed
US-9771317-B2 Process for preparing lacosamide and related compounds CAMBREX KARLSKOGA AB (SE) 2017-09-26 US disclosed
US-20150299105-A1 NEW PROCESS CAMBREX KARLSKOGA AB (SE) 2015-10-22 US disclosed
EP-2914574-A2 NEW PROCESS Cambrex Karlskoga Ab (SE) 2015-09-09 EP disclosed
WO-2014068333-A2 NEW PROCESS CAMBREX KARLSKOGA AB (SE) 2014-05-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299105-A1 NEW PROCESS SLC6A11, SLC6A1, SCN11A CA12 431/4885CA1 502/4885CA2 234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.