Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.34 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.34 |
| ▸ | MLYCD | O95822 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14830095 | 0.87 | MT-CO2 (0.44) | NPSR1HSD17B10MEN1KMT2A | |
| SCHEMBL3349318 | 0.82 | MLYCD (0.41) | KCNQ4KCNQ5MLYCDLTB4R2MEN1 | |
| SCHEMBL2900197 | 0.80 | KDM1A (0.42) | KDM1AHDAC8HDAC6KCNQ4KCNQ5 | |
| SCHEMBL8289776 | 0.78 | F2 (0.38) | KCNQ4KCNQ5MEN1KMT2A | |
| SCHEMBL8349153 | 0.76 | SSTR4 (0.43) | KCNQ4KCNQ5MLYCDLMNANPSR1 | |
| SCHEMBL9222980 | 0.75 | KCNQ4 (0.41) | KDM1AHDAC8HDAC6KCNQ4KCNQ5 | |
| SCHEMBL24232684 | 0.74 | POLQ (0.42) | KCNQ4KCNQ5LMNAHSD17B10POLQ | |
| SCHEMBL4664640 | 0.73 | SMN1; SMN2 (0.45) | L3MBTL1NPSR1MEN1KMT2AOPRM1 | |
| SCHEMBL3989317 | 0.73 | KMT2A (0.35) | KDM1AHDAC8HDAC6KCNQ4KCNQ5 | |
| SCHEMBL6217029 | 0.73 | MAPT (0.36) | KCNQ4KCNQ5MLYCDLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2912034-A1 | 3,4-DISUBSTITUTED OXAZOLIDINONE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE CALCIUM ACTIVATED POTASSIUM CHANNEL | F. Hoffmann-La Roche AG (CH) | 2015-09-02 | — | — | EP | disclosed |
| WO-2014067861-A1 | 3,4-DISUBSTITUTED OXAZOLIDINONE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE CALCIUM ACTIVATED POTASSIUM CHANNEL | F. HOFFMANN-LA ROCHE AG (CH) | 2014-05-08 | — | — | WO | disclosed |