Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ATP4A | P20648 | 3/20 | 0.33 |
| ▸ | ATP4B | P51164 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL992683 | 0.91 | LMNA (0.47) | LMNAATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL1567057 | 0.91 | LMNA (0.47) | LMNAATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL16813616 | 0.89 | LMNA (0.37) | LMNA | |
| SCHEMBL7938343 | 0.89 | LMNA (0.46) | LMNAATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL16424550 | 0.86 | LMNA (0.36) | LMNA | |
| SCHEMBL15657209 | 0.86 | LMNA (0.36) | LMNA | |
| SCHEMBL2840199 | 0.86 | LMNA (0.36) | LMNA | |
| SCHEMBL5173414 | 0.85 | LMNA (0.32) | LMNA | |
| SCHEMBL17800748 | 0.84 | LMNA (0.50) | LMNAKDM5AKCNH2 | |
| SCHEMBL16813493 | 0.84 | ALDH1A1 (0.36) | LMNAHSP90AA1HSP90AB1HRH3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369443-B1 | Positively chargeable developer | CANON KK (JP) | 1996-04-10 | — | — | EP | disclosed |
| EP-0365982-B1 | ACRYLIC RUBBER COMPOSITION | TORAY SILICONE COMPANY, LIMITED (JP) | 1993-07-14 | — | — | EP | disclosed |
| US-5002995-A | Roll workability, rapid vulcanization rate | TORAY SILICONE COMPANY, LIMITED (JP) | 1991-03-26 | — | — | US | disclosed |
| EP-0365982-A1 | Acrylic rubber composition | TORAY SILICONE COMPANY, LIMITED (JP) | 1990-05-02 | — | — | EP | disclosed |