Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.53 |
| ▸ | METAP1 | P53582 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740101 | 0.83 | ACHE (0.50) | ACHEMETAP1CYP19A1TSHRHTR1A | |
| SCHEMBL29850498 | 0.80 | ACHE (0.58) | ACHEMETAP1CYP19A1TSHRHTR2C | |
| SCHEMBL1567503 | 0.80 | ACHE (0.58) | ACHEMETAP1CYP19A1TSHRHTR2C | |
| SCHEMBL3602309 | 0.80 | ACHE (0.46) | ACHEMETAP1CYP19A1TSHRMAPT | |
| SCHEMBL10702063 | 0.79 | ACHE (0.49) | ACHEMETAP1CYP19A1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL6601125 | 0.79 | ACHE (0.56) | ACHEMETAP1CYP19A1TSHRHTR1A | |
| SCHEMBL11289312 | 0.78 | ACHE (0.44) | ACHEMETAP1CYP19A1TSHRHTR1A | |
| SCHEMBL1500370 | 0.78 | METAP1 (0.52) | ACHEMETAP1MAPT | |
| SCHEMBL866816 | 0.77 | METAP1 (0.67) | ACHEMETAP1CYP19A1HTR1ADRD2 | |
| SCHEMBL9495652 | 0.76 | MEN1 (0.45) | ACHEMETAP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701684-B2 | Chiral fluorinating reagents | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| US-20150284401-A1 | CHIRAL FLUORINATING REAGENTS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2015-10-08 | — | — | US | disclosed |
| EP-2914582-A2 | CHIRAL FLUORINATING REAGENTS | Isis Innovation Limited (GB) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014068341-A2 | CHIRAL FLUORINATING REAGENTS | ISIS INNOVATION LIMITED (GB) | 2014-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284401-A1 | CHIRAL FLUORINATING REAGENTS | TIAM1, AFF2, AFF1 | ACHE 3151/4885METAP1 3883/4885CYP19A1 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.