Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL7849032 | 0.98 | EGFR (0.77) | EGFRALDH1A1PIK3CDPIK3CANPC1 | |
| Quinoline SCHEMBL27927382 | 0.98 | EGFR (0.77) | EGFRALDH1A1PIK3CDPIK3CANPC1 | |
| Quinoline SCHEMBL27710462 | 0.94 | EGFR (0.71) | EGFRALDH1A1PIK3CDPIK3CANPC1 | |
| Isoquinoline SCHEMBL27889185 | 0.91 | EGFR (0.67) | EGFRALDH1A1PIK3CDPIK3CANPC1 | |
| Quinoxaline SCHEMBL150387 | 0.90 | EGFR (0.83) | EGFRALDH1A1PIK3CDPIK3CANPC1 | |
| Quinazoline SCHEMBL22833783 | 0.89 | EGFR (1.00) | EGFRALDH1A1PIK3CDPIK3CACYP2A6 | |
| Quinazoline SCHEMBL29356169 | 0.89 | EGFR (1.00) | EGFRALDH1A1PIK3CDPIK3CACYP2A6 | |
| Quinazoline SCHEMBL29490398 | 0.89 | EGFR (1.00) | EGFRALDH1A1PIK3CDPIK3CACYP2A6 | |
| Quinazoline SCHEMBL5920 | 0.89 | EGFR (1.00) | EGFRALDH1A1PIK3CDPIK3CACYP2A6 | |
| Quinazoline SCHEMBL28109843 | 0.88 | EGFR (0.87) | EGFRALDH1A1PIK3CDPIK3CANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541807-A | Novel quinazoline derivative LU1506, preparation method and applications thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-05-04 | — | — | CN | claimed |
| CN-105503747-A | Novel quinazoline derivative LU1507 as well as preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-04-20 | — | — | CN | claimed |
| CN-105503836-A | Novel quinazoline derivative LU1502 as well as preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-04-20 | — | — | CN | claimed |
| CN-105503835-A | Novel quinazoline derivative LU1510 as well as preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-04-20 | — | — | CN | claimed |
| CN-105481835-A | Novel quinazoline derivative LU1508, and preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-04-13 | — | — | CN | claimed |
| CN-105461642-A | Novel quinazoline derivative LU1505 as well as preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-04-06 | — | — | CN | claimed |
| CN-105418517-A | Novel quinazoline derivative LU1509 as well as preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-03-23 | — | — | CN | claimed |
| CN-105399733-A | Novel quinazoline derivative LU1504 and preparing method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-03-16 | — | — | CN | claimed |
| CN-105399689-A | Novel quinazoline derivative LU1503 and preparing method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-03-16 | — | — | CN | claimed |
| CN-105384699-A | Novel quinazoline derivative LU1501, as well as preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-03-09 | — | — | CN | claimed |
| EP-2611797-A2 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | Hanmi Science Co., Ltd. (KR) | 2013-07-10 | — | — | EP | claimed |
| CN-103155930-A | Insecticidal composition compounded with macrolide compound | HAILIR PESTICIDES & CHEM GROUP | 2013-06-19 | — | — | CN | claimed |
| CN-103130730-A | Novel quinazoline derivative, and preparation method, anti-HIV activity and anti-TMV activity thereof | UNIV NANKAI | 2013-06-05 | — | — | CN | claimed |
| CN-103125493-A | Insecticide composition mixed with amides pesticide | HAILIR PESTCIDES AND CHEMICALS GROUP CO LTD | 2013-06-05 | — | — | CN | claimed |
| CN-103125496-A | Novel insecticide composition compounding pymetrozine | JIANGXI HAIKE RUITE CROP SCIENCE CO LTD | 2013-06-05 | — | — | CN | claimed |
| CN-102440257-A | Insecticidal composition compounded with partial nicotine compounds | HAILIR PESTICIDES & CHEM GROUP | 2012-05-09 | — | — | CN | claimed |
| CN-102428922-A | Insecticidal composition compounded with bishydrazide pesticide | HAILIR PESTICIDES & CHEMICALS GROUP CO LTD | 2012-05-02 | — | — | CN | claimed |
| CN-102415394-A | High-efficiency insecticidal composition containing indoxacarb | HAILIR PESTICIDES & CHEM GROUP | 2012-04-18 | — | — | CN | claimed |
| WO-2012030160-A2 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | HANMI HOLDINGS CO., LTD. (KR) | 2012-03-08 | — | — | WO | claimed |
| WO-2024052340-A1 | PREDICTION OF PHARMACOKINETIC PROPERTIES OF CHEMICAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-03-14 | — | — | WO | disclosed |
| CN-114040909-A | Process for the preparation of XPO1 inhibitors and intermediates useful in the preparation of XP01 inhibitors | 卡尔约药物治疗公司 | 2022-02-11 | — | — | CN | disclosed |
| EP-3897651-A1 | DISCOVERY OF BD OXIDASE INHIBITORS FOR THE TREATMENT OF MYCOBACTERIAL DISEASES | University of Notre Dame du Lac (US) | 2021-10-27 | — | — | EP | disclosed |
| CN-112442032-B | Preparation method of medicine intermediate benzopyrimidinoquinolinone derivative | 南京苏亦欣医药科技有限公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-106458933-B | Quinazoline scaffold-based compounds, pharmaceutical compositions thereof, and methods of use | 泰克年研究发展基金会公司 | 2021-03-05 | — | — | CN | disclosed |
| CN-112442032-A | Preparation method of medicine intermediate benzopyrimidinoquinolinone derivative | 南京苏亦欣医药科技有限公司 | 2021-03-05 | — | — | CN | disclosed |
| WO-2020128981-A1 | DISCOVERY OF BD OXIDASE INHIBITORS FOR THE TREATMENT OF MYCOBACTERIAL DISEASES | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2020-06-25 | — | — | WO | disclosed |
| CN-108047206-B | Pivaloyl amino benzo [d] azepine * base quinazoline compounds and preparation and application | 浙江工业大学 | 2019-11-29 | — | — | CN | disclosed |
| CN-108033949-B | 6- (2- dipropyl aminoacetylamino) quinazoline compounds and preparation and application | 浙江工业大学 | 2019-11-29 | — | — | CN | disclosed |
| CN-108084162-B | Dimethoxy benzene aminoacetylamino benzo [d] azepine * base quinazoline compounds and preparation and application | 浙江工业大学 | 2019-11-29 | — | — | CN | disclosed |
| CN-105283454-B | Quinazoline and azepine quinazoline as RAS/RAF/MEK/ERK and PI3K/AKT/PTEN/MTOR access double inhibitor | ASANA BIOSCIENCES, LLC (US) | 2019-10-29 | — | — | CN | disclosed |
| CN-110343090-A | Quinazoline derivant salt form crystal form and preparation method and application | 威尚（上海）生物医药有限公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-110256363-A | A kind of preparation method and application of the EGFR inhibitor containing quinazoline structure | 宿州学院 | 2019-09-20 | — | — | CN | disclosed |
| CN-110250186-A | Synergetic pesticide composition containing pyridine quinazoline | 江西中迅农化有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110229109-A | A kind of preparation method of 4- methylene quinazoline (sulphur) ketone compounds | 台州学院 | 2019-09-13 | — | — | CN | disclosed |
| CN-110156704-A | 1,2,4- triazole sulfide derivative and its crystal structure and application | 湖南大学 | 2019-08-23 | — | — | CN | disclosed |
| CN-110092781-A | A kind of novel quinazoline quinoline class EGFR inhibitor and its preparation and application | 河南省医药科学研究院 | 2019-08-06 | — | — | CN | disclosed |
| CN-110092781-A | A kind of novel quinazoline quinoline class EGFR inhibitor and its preparation and application | 河南省医药科学研究院 | 2019-08-06 | — | — | CN | disclosed |
| CN-110092781-A | A kind of novel quinazoline quinoline class EGFR inhibitor and its preparation and application | 河南省医药科学研究院 | 2019-08-06 | — | — | CN | disclosed |
| CN-109705094-A | A kind of preparation method of pyridine quinazoline | 湖南速博生物技术有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-106632087-B | Preparation method of 4-aryl-2- (2- (sulfur trifluoromethyl) aryl) quinazoline | 江西师范大学 | 2019-03-08 | — | — | CN | disclosed |
| CN-109310683-A | Small molecule dual inhibitors of TRPV4 and TRPA1 for disinfection and anesthesia | 杜克大学 | 2019-02-05 | — | — | CN | disclosed |
| CN-109251196-A | Amino benzo [d] azepine * base quinazoline compounds and its preparation method and application | 浙江工业大学 | 2019-01-22 | — | — | CN | disclosed |
| CN-109122703-A | A kind of composition pesticide of quinazoline containing pyridine and double third ring worm esters | 江西中迅农化有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-109122693-A | The Pesticidal combination of quinazoline containing pyridine and four chlorantraniliproles | 湖南农大海特农化有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-109053598-A | A kind of aryl substituted quinazoline compounds and its synthetic method | 温州大学 | 2018-12-21 | — | — | CN | disclosed |
| CN-109053599-A | 4-aryl-2- (2- (sulfur trifluoromethyl) aryl) quinazoline compound | 江西师范大学 | 2018-12-21 | — | — | CN | disclosed |
| CN-109053597-A | A kind of inflammation inhibiting compound and preparation method thereof | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 2018-12-21 | — | — | CN | disclosed |
| CN-108976173-A | Preparation method of 4-aryl-2- (2- (sulfur trifluoromethyl) aryl) quinazoline | 江西师范大学 | 2018-12-11 | — | — | CN | disclosed |
| CN-108912060-A | A kind of quinazoline ditosylate salt anti-inflammatory compound and its synthetic method | 温州医科大学 | 2018-11-30 | — | — | CN | disclosed |
| CN-108912061-A | A kind of synthetic method of quinazoline ditosylate salt inflammation inhibiting compound | 温州医科大学 | 2018-11-30 | — | — | CN | disclosed |
| CN-108912059-A | A kind of synthetic method of nitrogen-containing heterocycle inflammation inhibiting compound | 温州医科大学附属第医院 | 2018-11-30 | — | — | CN | disclosed |
| CN-108863950-A | A kind of diaryl substituted quinazoline compounds and its synthetic method | 温州大学 | 2018-11-23 | — | — | CN | disclosed |
| CN-108849961-A | Composition pesticide containing pyridine quinazoline | 江西中迅农化有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108727283-A | A kind of synthetic method of benzene sulfonyl Ammonia anti-inflammatory compound | 温州医科大学附属第医院 | 2018-11-02 | — | — | CN | disclosed |
| CN-108727282-A | A kind of anti-inflammatory compound and its synthetic method containing benzenesulfonamido- | 温州医科大学附属第医院 | 2018-11-02 | — | — | CN | disclosed |
| CN-106749280-B | 5H- quinazolines [3,2-b] cinnolines -7,13- cyclohexadione compounds and preparation method thereof | 河南师范大学 | 2018-09-18 | — | — | CN | disclosed |
| CN-105481835-B | A kind of quinazoline derivant LU1508 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-09-04 | — | — | CN | disclosed |
| CN-105481835-B | A kind of quinazoline derivant LU1508 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-09-04 | — | — | CN | disclosed |
| CN-104814028-B | Composition pesticide containing pyridine quinazoline and Moroxydine Hydrochloride | 广州万粤知识产权运营有限公司 | 2018-08-14 | — | — | CN | disclosed |
| CN-104824009-B | Pesticidal combination containing pyridine quinazoline and sulfoxaflor | 广东中迅农科股份有限公司 | 2018-08-14 | — | — | CN | disclosed |
| CN-108378046-A | A kind of Pesticidal combination containing pyridine quinazoline and Buprofezin | 安徽省农业科学院植物保护与农产品质量安全研究所 | 2018-08-10 | — | — | CN | disclosed |
| CN-108324719-A | Adjacent toluidino acetylamino anisyl benzo-aza * bases quinazoline compounds are preparing the application in treating uterine neck cancer drug | 浙江工业大学 | 2018-07-27 | — | — | CN | disclosed |
| CN-108324717-A | Pivaloyl amino chloro benzo [d] azepine * bases quinazoline compounds are preparing the application in treating uterine neck cancer drug | 浙江工业大学 | 2018-07-27 | — | — | CN | disclosed |
| CN-108329299-A | Butyrylamino chloro benzo [ d ] aza-based quinazoline compound, preparation and application thereof | 浙江工业大学 | 2018-07-27 | — | — | CN | disclosed |
| CN-108329300-A | Nitro benzo [d] azepine * base quinazoline compounds and its preparation method and application | 浙江工业大学 | 2018-07-27 | — | — | CN | disclosed |
| CN-108324718-A | Application of the cyclohexyl methoxy formamido group chloro benzo azepine * bases quinazoline compounds in treating leukemia medicament | 浙江工业大学 | 2018-07-27 | — | — | CN | disclosed |
| CN-108309984-A | Propionamido quinazoline compounds are preparing the application in treating uterine neck cancer drug | 浙江工业大学 | 2018-07-24 | — | — | CN | disclosed |
| CN-108295076-A | Propionamido dimethoxy benzo [d] azepine * bases quinazoline ditosylate salt is preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-07-20 | — | — | CN | disclosed |
| CN-108276384-A | Acetylamino benzo [d] azepine * bases quinazoline compounds and its preparation and application | 浙江工业大学 | 2018-07-13 | — | — | CN | disclosed |
| CN-108276385-A | Isobutyryl amino-quinazoline compound and its preparation and application | 浙江工业大学 | 2018-07-13 | — | — | CN | disclosed |
| CN-108276386-A | Cyclohexyl methoxy formamido group quinazoline compounds and preparation and application | 浙江工业大学 | 2018-07-13 | — | — | CN | disclosed |
| CN-108245521-A | Dipropyl aminoacetylamino benzo-aza * bases quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-108250185-A | 6- (2- (adjacent toluidino) acetylamino) quinazoline compounds and preparation and application | 浙江工业大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-108245519-A | Application of butyrylaminoquinazoline compound in preparation of drugs for treating leukemia | 浙江工业大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-108245520-A | Acetylamino quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-108186649-A | Propionamido chloro benzo [d] azepine * bases quinazoline ditosylate salt is preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-06-22 | — | — | CN | disclosed |
| CN-108164510-A | Chloro acetylamino benzo [d] azepine * base quinazoline compounds and its preparation method and application | 浙江工业大学 | 2018-06-15 | — | — | CN | disclosed |
| CN-108143736-A | Application of butyrylaminobenzo [ d ] aza-based quinazoline in preparation of drugs for treating lung cancer | 浙江工业大学 | 2018-06-12 | — | — | CN | disclosed |
| CN-108125961-A | Morpholinyl acetylamino anisyl benzo-aza * bases quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108125962-A | Benzo [d] azepine * bases quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108129461-A | Benzamido benzo [d] azepine * bases quinazoline compounds and preparation and application | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108125959-A | Dimethoxy benzene aminoacetylamino quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108125960-A | Isobutyryl amino benzo [d] azepine * bases quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108129460-A | Anisyl benzo [d] azepine * bases quinazoline compounds and preparation and application | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108125958-A | Adjacent toluidino acetylamino chloro benzo azepine * bases quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108117542-A | Propionamido anisyl benzo [d] azepine * bases quinazoline compounds and preparation and application | 浙江工业大学 | 2018-06-05 | — | — | CN | disclosed |
| CN-108078995-A | Benzamido quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-108078992-A | Pivaloyl amino dimethoxy benzo [d] azepine * bases quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-108084162-A | Dimethoxy benzene aminoacetylamino benzo [d] azepine * bases quinazoline compounds and preparation and application | 浙江工业大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-108078994-A | 6- (2- morpholinyls acetylamino) quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-108078993-A | 6- nitro-quinazoline class compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-108042546-A | Morpholinyl acetylamino benzo [d] azepine * bases quinazoline compounds are preparing the application in treating uterine neck cancer drug | 浙江工业大学 | 2018-05-18 | — | — | CN | disclosed |
| CN-108047206-A | Pivaloyl amino benzo [d] azepine * bases quinazoline compounds and preparation and application | 浙江工业大学 | 2018-05-18 | — | — | CN | disclosed |
| CN-108033949-A | 6- (2- dipropyls aminoacetylamino) quinazoline compounds and preparation and application | 浙江工业大学 | 2018-05-15 | — | — | CN | disclosed |
| CN-108014113-A | Application of butyrylamidodimethoxybenzo [ d ] aza-based quinazoline compound in preparation of drugs for treating cervical cancer | 浙江工业大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-108014114-A | Chloro acetylamino quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-108014115-A | Pivaloyl amino anisyl benzo [d] azepine * bases quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-108014112-A | Adjacent toluidino acetylamino benzo [d] azepine * bases quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-108017621-A | Morpholinyl acetylamino dimethoxy benzo [d] azepine * bases quinazoline compounds and preparation and application | 浙江工业大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-108014116-A | Amino dimethoxy benzo [d] azepine * bases quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-104876882-B | 6- amino-quinazoline compounds and application | 浙江工业大学 | 2018-05-08 | — | — | CN | disclosed |
| CN-104824011-B | Pesticidal combination containing pyridine quinazoline and guadipyr | 广东中迅农科股份有限公司 | 2018-04-27 | — | — | CN | disclosed |
| CN-105541807-B | A kind of novel quinazoline quinoline derivant LU1506 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-04-24 | — | — | CN | disclosed |
| CN-105541807-B | A kind of novel quinazoline quinoline derivant LU1506 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-04-24 | — | — | CN | disclosed |
| CN-105541807-B | A kind of novel quinazoline quinoline derivant LU1506 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-04-24 | — | — | CN | disclosed |
| CN-105503836-B | A kind of novel quinazoline quinoline derivant LU1502 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-04-24 | — | — | CN | disclosed |
| CN-105399733-B | A kind of novel quinazoline quinoline derivant LU1504 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-04-24 | — | — | CN | disclosed |
| CN-105399733-B | A kind of novel quinazoline quinoline derivant LU1504 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-04-24 | — | — | CN | disclosed |
| CN-105399733-B | A kind of novel quinazoline quinoline derivant LU1504 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-04-24 | — | — | CN | disclosed |
| CN-105503836-B | A kind of novel quinazoline quinoline derivant LU1502 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-04-24 | — | — | CN | disclosed |
| CN-105503836-B | A kind of novel quinazoline quinoline derivant LU1502 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-04-24 | — | — | CN | disclosed |
| CN-105503835-B | A kind of novel quinazoline quinoline derivant LU1510 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-04-24 | — | — | CN | disclosed |
| CN-105503835-B | A kind of novel quinazoline quinoline derivant LU1510 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-04-24 | — | — | CN | disclosed |
| CN-105503835-B | A kind of novel quinazoline quinoline derivant LU1510 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2018-04-24 | — | — | CN | disclosed |
| CN-107892684-A | Quinazoline derivant and its pharmaceutical composition, and the purposes as medicine | 锦州奥鸿药业有限责任公司 | 2018-04-10 | — | — | CN | disclosed |
| CN-104738046-B | Pesticidal combination containing pyridine quinazoline and chlorine fluorine cyanogen insect amide | 广东中迅农科股份有限公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-105503747-B | A kind of quinazoline derivant LU1507 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2017-12-19 | — | — | CN | disclosed |
| CN-105705494-B | Quinazoline derivatives, pharmaceutical compositions thereof, and use as medicaments | 锦州奥鸿药业有限责任公司 | 2017-12-15 | — | — | CN | disclosed |
| CN-104926737-B | 4 (3 substituted anilinic) 6 substituent quinazoline compounds and preparation and application | 浙江工业大学 | 2017-11-07 | — | — | CN | disclosed |
| CN-106749280-A | 5H quinazolines [3,2 b] cyclohexadione compounds of cinnolines 7,13 and preparation method thereof | 河南师范大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-106632087-A | Preparation method of 4-aryl-2- (2- (sulfur trifluoromethyl) aryl) quinazoline | 江西师范大学 | 2017-05-10 | — | — | CN | disclosed |
| CN-103998040-B | The quinazoline compound and its using method of alkynyl substituted | 江苏康缘药业股份有限公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-105418517-B | Novel quinazoline derivative LU1509 as well as preparation method and application thereof | 中国人民解放军南京军区南京总医院 | 2017-03-22 | — | — | CN | disclosed |
| CN-105461642-B | Novel quinazoline derivative LU1505 as well as preparation method and application thereof | 中国人民解放军南京军区南京总医院 | 2017-03-22 | — | — | CN | disclosed |
| CN-105399689-B | A kind of novel quinazoline quinoline derivant LU1503 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2017-03-01 | — | — | CN | disclosed |
| CN-105399689-B | A kind of novel quinazoline quinoline derivant LU1503 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2017-03-01 | — | — | CN | disclosed |
| CN-105399689-B | A kind of novel quinazoline quinoline derivant LU1503 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2017-03-01 | — | — | CN | disclosed |
| CN-105384699-B | A kind of novel quinazoline quinoline derivant LU1501 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2016-10-12 | — | — | CN | disclosed |
| CN-105384699-B | A kind of novel quinazoline quinoline derivant LU1501 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2016-10-12 | — | — | CN | disclosed |
| CN-105384699-B | A kind of novel quinazoline quinoline derivant LU1501 and its preparation method and application | 中国人民解放军南京军区南京总医院 | 2016-10-12 | — | — | CN | disclosed |
| CN-105837564-A | Pyridine-containing benzothiazepine derivatives, and preparation method and application thereof | 贵州大学 | 2016-08-10 | — | — | CN | disclosed |
| CN-104350049-B | Substituted-amino quinazoline as inhibitors of kinases | 苏州韬略生物科技有限公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-104292170-B | There is quinazoline-Arylurea derivatives and the application thereof of antitumor action | 广西师范大学 | 2016-06-29 | — | — | CN | disclosed |
| CN-105705494-A | Quinazoline derivatives, pharmaceutical compositions thereof, and use as medicaments | 锦州奥鸿药业有限责任公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-105541807-A | Novel quinazoline derivative LU1506, preparation method and applications thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-05-04 | — | — | CN | disclosed |
| CN-105503747-A | Novel quinazoline derivative LU1507 as well as preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-04-20 | — | — | CN | disclosed |
| CN-105503835-A | Novel quinazoline derivative LU1510 as well as preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-04-20 | — | — | CN | disclosed |
| CN-105503836-A | Novel quinazoline derivative LU1502 as well as preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-04-20 | — | — | CN | disclosed |
| CN-105475287-A | Insecticidal composition containing pyridine quinazoline and trifluoro-benzene pyrimidine | GUANGDONG ZHONGXUN AGRICULTURAL TECH CO LTD | 2016-04-13 | — | — | CN | disclosed |
| CN-105481835-A | Novel quinazoline derivative LU1508, and preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-04-13 | — | — | CN | disclosed |
| CN-105461642-A | Novel quinazoline derivative LU1505 as well as preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-04-06 | — | — | CN | disclosed |
| CN-105418517-A | Novel quinazoline derivative LU1509 as well as preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-03-23 | — | — | CN | disclosed |
| CN-105399733-A | Novel quinazoline derivative LU1504 and preparing method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-03-16 | — | — | CN | disclosed |
| CN-105399689-A | Novel quinazoline derivative LU1503 and preparing method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-03-16 | — | — | CN | disclosed |
| CN-102887891-B | N4-phenyl-quinazoline-4-sulfonamide derivatives and related compound | ARRAY BIOPHARMA INC. (US) | 2016-03-09 | — | — | CN | disclosed |
| CN-103980209-B | A kind of 4-N-replaces-5-chloro-quinazoline compounds and preparation method and application | GUIZHOU UNIVERSITY (CN) | 2016-03-09 | — | — | CN | disclosed |
| CN-105384699-A | Novel quinazoline derivative LU1501, as well as preparation method and application thereof | NANJING GENERAL HOSPITAL NANJING MILITARY AREA COMMAND PLA | 2016-03-09 | — | — | CN | disclosed |
| CN-105339009-A | Combination therapy comprising a TOR kinase inhibitor and a 5-substituted quinazolinone compound for treating cancer | SIGNAL PHARM LLC | 2016-02-17 | — | — | CN | disclosed |
| CN-104824015-A | Agricultural composition containing pyridine quinazoline and dufulin | GUANGDONG ZHONGXUN AGRI TECH | 2015-08-12 | — | — | CN | disclosed |
| CN-104824011-A | Insecticidal composition containing pyridine quinazoline and guadipyr | GUANGDONG ZHONGXUN AGRI TECH | 2015-08-12 | — | — | CN | disclosed |
| CN-104824009-A | Insecticidal composition containing pyridine quinazoline and sulfoxaflor | GUANGDONG ZHONGXUN AGRI TECH | 2015-08-12 | — | — | CN | disclosed |
| CN-104814028-A | Pesticide composition containing pyridine quinazoline and moroxydine hydrochloride | GUANGDONG ZHONGXUN AGRI TECH | 2015-08-05 | — | — | CN | disclosed |
| CN-104756992-A | Insecticide composition containing pyridine quinazoline and chloro-chlorfenapyr | GUANGDONG ZHONGXUN AGRI TECH | 2015-07-08 | — | — | CN | disclosed |
| CN-104738046-A | Insecticidal composition containing pyridine quinazoline and cyhalodiamide | GUANGDONG ZHONGXUN AGRI TECH | 2015-07-01 | — | — | CN | disclosed |
| CN-103130730-B | Novel quinazoline derivative, and preparation method, anti-HIV activity and anti-TMV activity thereof | UNIV NANKAI | 2015-04-08 | — | — | CN | disclosed |
| CN-103435558-B | Synthetic method of quinazoline derivative | UNIV WENZHOU | 2015-04-08 | — | — | CN | disclosed |
| CN-104292170-A | Quinazolinyl-aryl urea derivatives with antitumor function and application thereof | UNIV GUANGXI NORMAL | 2015-01-21 | — | — | CN | disclosed |
| CN-104193581-A | Compound for organic thin film transistor and organic thin film transistor using the same | IDEMITSU KOSAN CO | 2014-12-10 | — | — | CN | disclosed |
| CN-104098551-A | Substituted quinazoline derivative as aurora kinase inhibitor | GUANGDONG HEC PHARMACEUTICAL | 2014-10-15 | — | — | CN | disclosed |
| CN-104069112-A | Substituted piperidino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INT | 2014-10-01 | — | — | CN | disclosed |
| CN-102079759-B | 6-substituted quinazoline derivative, preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2014-09-17 | — | — | CN | disclosed |
| CN-103012291-B | 2-phenyl quinazoline derivative, preparation method thereof, and application in preparation of anti-cancer drugs | UNIV SUN YAT SEN | 2014-09-03 | — | — | CN | disclosed |
| CN-103998040-A | Alkyne substituted quinazoline compound and methods of use | NEWGEN THERAPEUTICS INC | 2014-08-20 | — | — | CN | disclosed |
| CN-103980209-A | 4-N-substituted-5-chloroquinazoline compound and preparation method and application thereof | UNIV GUIZHOU | 2014-08-13 | — | — | CN | disclosed |
| CN-102532103-B | Quinazolinyl aryl urea derivatives and preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2014-07-09 | — | — | CN | disclosed |
| CN-103842346-A | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG | 2014-06-04 | — | — | CN | disclosed |
| CN-103613553-A | S-triazole Schiff base bisamide derivative as well as preparation method and usage thereof | XINGYI NORMAL UNIVERSITY FOR NATIONALITIES | 2014-03-05 | — | — | CN | disclosed |
| CN-101501007-B | Quinazoline derivative | ASKA PARMACEUTICAL CO LTD | 2014-01-29 | — | — | CN | disclosed |
| CN-103467388-A | Method for synthesizing aryl or heteroaryl substituted quinazoline compound | UNIV WENZHOU | 2013-12-25 | — | — | CN | disclosed |
| CN-102146076-B | Anilinoquinazoline derivatives and preparation method thereof | UNIV SHANXI NORMAL | 2013-12-25 | — | — | CN | disclosed |
| CN-103435558-A | Synthetic method of quinazoline derivative | UNIV WENZHOU | 2013-12-11 | — | — | CN | disclosed |
| CN-101367793-B | Amino-quinazoline derivative with antineoplastic activity and salts thereof | GUANGZHOU INST BIOMED & HEALTH | 2013-09-11 | — | — | CN | disclosed |
| CN-103155930-A | Insecticidal composition compounded with macrolide compound | HAILIR PESTICIDES & CHEM GROUP | 2013-06-19 | — | — | CN | disclosed |
| CN-103130730-A | Novel quinazoline derivative, and preparation method, anti-HIV activity and anti-TMV activity thereof | UNIV NANKAI | 2013-06-05 | — | — | CN | disclosed |
| CN-103125493-A | Insecticide composition mixed with amides pesticide | HAILIR PESTCIDES AND CHEMICALS GROUP CO LTD | 2013-06-05 | — | — | CN | disclosed |
| CN-103125496-A | Novel insecticide composition compounding pymetrozine | JIANGXI HAIKE RUITE CROP SCIENCE CO LTD | 2013-06-05 | — | — | CN | disclosed |
| CN-101967127-B | Quinazoline derivative and preparation method thereof and application of quinazoline derivative for preparing anticancer drugs | UNIV SUN YAT SEN | 2013-05-29 | — | — | CN | disclosed |
| EP-2580217-A2 | 6-(ETHYNYL)PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONES FOR THE TREATMENT OF CNS DISORDERS | Afraxis, Inc. (US) | 2013-04-17 | — | — | EP | disclosed |
| CN-103012291-A | 2-phenyl quinazoline derivative, preparation method thereof, and application in preparation of anti-cancer drugs | UNIV SUN YAT SEN | 2013-04-03 | — | — | CN | disclosed |
| CN-102933579-A | New ccr2 receptor antagonists and uses thereof | BOEHRINGER INGELHEIM INT | 2013-02-13 | — | — | CN | disclosed |
| CN-102887891-A | N4-phenyl-quinaz0line-4 -amine derivatives and related compounds | ARRAY BIOPHARMA INC | 2013-01-23 | — | — | CN | disclosed |
| CN-102875481-A | 4-[2-(substituted benzylidene) hydrazino]-5, 6, 7-trialkoxy quinazoline compound and preparation method and application | UNIV GUIZHOU | 2013-01-16 | — | — | CN | disclosed |
| CN-101304978-B | Quinazoline derivative as multi-component inhibitor, pharmaceutical composition and application | HANMI PHARM IND CO LTD | 2012-12-26 | — | — | CN | disclosed |
| CN-101094840-B | Quinazoline derivatives for inhibiting the growth of cancer cells and methods for preparing the same | HANMI PHARM IND CO LTD | 2012-10-31 | — | — | CN | disclosed |
| CN-102712669-A | Ion pair soft salt based on organic metal complex and application thereof in organic light-emitting diode | UNIV SOUTHERN CALIFORNIA | 2012-10-03 | — | — | CN | disclosed |
| CN-102627614-A | Diquinazoline diselenide compound as well as preparation method and bioactivity thereof | UNIV LUDONG | 2012-08-08 | — | — | CN | disclosed |
| CN-102532103-A | Quinazolinyl aryl urea derivatives and preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2012-07-04 | — | — | CN | disclosed |
| CN-102440257-A | Insecticidal composition compounded with partial nicotine compounds | HAILIR PESTICIDES & CHEM GROUP | 2012-05-09 | — | — | CN | disclosed |
| CN-102428922-A | Insecticidal composition compounded with bishydrazide pesticide | HAILIR PESTICIDES & CHEMICALS GROUP CO LTD | 2012-05-02 | — | — | CN | disclosed |
| CN-1956966-B | Quinazoline derivatives and their therapeutic use | REXAHN CORP | 2012-04-18 | — | — | CN | disclosed |
| CN-102415394-A | High-efficiency insecticidal composition containing indoxacarb | HAILIR PESTICIDES & CHEM GROUP | 2012-04-18 | — | — | CN | disclosed |
| WO-2011156786-A2 | 6-(ETHYNYL)PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONES FOR THE TREATMENT OF CNS DISORDERS | AFRAXIS, INC. (US) | 2011-12-15 | — | — | WO | disclosed |
| CN-102146076-A | Novel anilinoquinazoline derivatives and preparation method thereof | UNIV SHANXI NORMAL | 2011-08-10 | — | — | CN | disclosed |
| CN-102079759-A | 6-substituted quinazoline derivative, preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2011-06-01 | — | — | CN | disclosed |
| CN-102060875-A | Novel quinazoline derivative, and preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2011-05-18 | — | — | CN | disclosed |
| US-20110092476-A1 | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof | RENOVIS, INC. | 2011-04-21 | — | — | US | disclosed |
| CN-101115470-B | Two-piece capsule comprising a preliminary closure for accommodating pharmaceutical preparations for powder inhalers | BOEHRINGER INGELHEIM INT | 2011-04-20 | — | — | CN | disclosed |
| CN-101967127-A | Quinazoline derivative and preparation method thereof and application of quinazoline derivative for preparing anticancer drugs | UNIV ZHONGSHAN | 2011-02-09 | — | — | CN | disclosed |
| CN-1809357-B | Small molecule Toll-like receptor (TLR) antagonists | COLEY PHARM GMBH | 2010-12-22 | — | — | CN | disclosed |
| CN-101787019-A | Quinazoline derivant | ASTRAZENECA AB | 2010-07-28 | — | — | CN | disclosed |
| CN-100577658-C | Quinazoline derivatives | ASTRAZENECA AB | 2010-01-06 | — | — | CN | disclosed |
| CN-101501007-A | Quinazoline derivative | ASKA PARMACEUTICAL CO LTD (JP) | 2009-08-05 | — | — | CN | disclosed |
| CN-100491372-C | Substituted quinazoline derivatives as inhibitors of aurora kinase | ASTRAZENECA AB (SE) | 2009-05-27 | — | — | CN | disclosed |
| CN-101437810-A | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2009-05-20 | — | — | CN | disclosed |
| CN-101367793-A | Amino-quinazoline derivative with antineoplastic activity and its salts | GUANGZHOU INST BIOMED & HEALTH (CN) | 2009-02-18 | — | — | CN | disclosed |
| CN-101321768-A | 4-anilino-substituted quinazoline derivatives as tyrosine kinase inhibitors | ASTRAZENECA AB (SE) | 2008-12-10 | — | — | CN | disclosed |
| CN-101321739-A | Quinazoline derivatives used as inhibitors of erbB tyrosine kinase | ASTRAZENECA AB (SE) | 2008-12-10 | — | — | CN | disclosed |
| CN-101304978-A | Quinazoline derivatives as multiplex inhibitors and process for their preparation | HANMI PHARM IND CO LTD (KR) | 2008-11-12 | — | — | CN | disclosed |
| CN-101094840-A | Quinazoline derivatives for inhibiting the growth of cancer cells and methods for preparing the same | HANMI PHARM IND CO LTD (KR) | 2007-12-26 | — | — | CN | disclosed |
| CN-100343238-C | Quinazoline derivatives as antitumor agents | ASTRAZENECA AB (SE) | 2007-10-17 | — | — | CN | disclosed |
| CN-1956966-A | Quinazoline derivatives and their therapeutic use | REXAHAN CORP (US) | 2007-05-02 | — | — | CN | disclosed |
| CN-1906178-A | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2007-01-31 | — | — | CN | disclosed |
| CN-1886399-A | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2006-12-27 | — | — | CN | disclosed |
| CN-1809357-A | Small molecule Toll-like receptor (TLR) antagonists | COLEY PHARM GROUP INC (DE) | 2006-07-26 | — | — | CN | disclosed |
| CN-1764651-A | Quinazoline derivatives as antitumor agents | ASTRAZENECA AB (SE) | 2006-04-26 | — | — | CN | disclosed |
| WO-2005065074-A2 | PROTECTION OF TISSUES AND CELLS FROM CYTOTOXIC EFFECTS OF IONIZING RADIATION BY ABL INHIBITORS | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2005-07-21 | — | — | WO | disclosed |
| CN-1620296-A | Substituted quinazoline derivatives as inhibitors of aurora kinases | ASTRAZENECA AB (SE) | 2005-05-25 | — | — | CN | disclosed |
| CN-1597671-A | Quinazoline deriative and preparation method and bioactivity | UNIV GUIZHOU (CN) | 2005-03-23 | — | — | CN | disclosed |
| CN-1585754-A | Quinazoline derivatives as antitumor agents | ASTRAZENECA AB (SE) | 2005-02-23 | — | — | CN | disclosed |
| WO-2004072046-A2 | QUINOLINE DERIVATIVES AND THEIR USE FOR MODULATION OF LXR ACTIVITY | CAREX S.A. (FR) | 2004-08-26 | — | — | WO | disclosed |
| CN-1158716-C | Electrodes for secondary cells, process for their production, and secondary cells having such electrodes | ������������ʽ���� | 2004-07-21 | — | — | CN | disclosed |
| CN-1489581-A | Quinazolinone derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-04-14 | — | — | CN | disclosed |
| CN-1058265-C | Quinazoline derivatives | YUHAN CORP (KR) | 2000-11-08 | — | — | CN | disclosed |
| CN-1143839-A | Electrodes for secondary cells, process for their production, and secondary cells having such electrodes | CANON KK (JP) | 1997-02-26 | — | — | CN | disclosed |
| CN-1113912-A | Quinazoline derivatives | — | 1995-12-27 | — | — | CN | disclosed |
| CN-1113912-A | Quinazoline derivatives | — | 1995-12-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092476-A1 | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof | P2RX7, P2RX3, P2RX2 | EGFR 4721/4885ALDH1A1 3640/4885PIK3CD 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.