Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15680349 | 0.88 | POLB (0.47) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL29556671 | 0.88 | POLB (0.47) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL9356550 | 0.88 | POLB (0.52) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL20886449 | 0.86 | POLB (0.47) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL29556668 | 0.86 | POLB (0.47) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL12381629 | 0.85 | MAOB (0.50) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL14699786 | 0.84 | MAPT (0.48) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL15495478 | 0.84 | LMNA (0.47) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL17191989 | 0.84 | POLB (0.43) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL17191987 | 0.84 | POLB (0.43) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019070052-A1 | NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUND OR SALT, AND APPLICATION THEREOF | 富士フイルム株式会社 | 2019-04-11 | — | — | WO | disclosed |
| WO-2014068388-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2014-05-08 | — | — | WO | disclosed |