Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556671 | 1.00 | POLB (0.47) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL21456035 | 0.90 | POLB (0.45) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL29557301 | 0.90 | POLB (0.45) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL9356550 | 0.90 | POLB (0.52) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL20886449 | 0.88 | POLB (0.47) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL29556668 | 0.88 | POLB (0.47) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL15680328 | 0.88 | POLB (0.45) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL12381629 | 0.87 | MAOB (0.50) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL15680534 | 0.87 | POLB (0.43) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL21456202 | 0.87 | MTNR1A (0.43) | POLBNPC1RAB9ASMN1; SMN2PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4039257-B1 | PHARMACEUTICAL COMPOSITION AND KIT CONTAINING A PENAM DERIVATIVE OR SALT THEREOF AND ONE OR MORE COMPOUNDS SELECTED FROM BETA-LACTAMASE INHIBITOR COMPOUND, ANTIBACTERIAL COMPOUND AND SALTS OF THESE | FUJIFILM CORP (JP) | 2026-05-27 | — | — | EP | disclosed |
| US-12286440-B2 | Penam derivative or salt thereof, pharmaceutical composition, and applications thereof | FUJIFILM CORPORATION (JP) | 2025-04-29 | — | — | US | disclosed |
| CN-111954673-B | New penam derivatives or salts thereof, pharmaceutical compositions and uses thereof | 富士胶片株式会社 | 2023-09-05 | — | — | CN | disclosed |
| EP-4039257-A1 | PHARMACEUTICAL COMPOSITION AND KIT CHARACTERIZED BY CONTAINING NOVEL PENAM DERIVATIVE OR SALT THEREOF AND ONE OR MORE COMPOUNDS SELECTED FROM ?-LACTAMASE INHIBITOR COMPOUND, ANTIBACTERIAL COMPOUND AND SALTS OF THESE | FUJIFILM Corporation (JP) | 2022-08-10 | — | — | EP | disclosed |
| US-20220241249-A1 | PHARMACEUTICAL COMPOSITION AND KIT CONTAINING NOVEL PENAM DERIVATIVE OR SALT THEREOF AND ONE OR MORE COMPOUNDS SELECTED FROM beta-LACTAMASE INHIBITORY COMPOUND AND ANTIBACTERIAL COMPOUND OR SALTS THEREOF | FUJIFILM CORPORATION (JP) | 2022-08-04 | — | — | US | disclosed |
| CN-114531850-A | Pharmaceutical composition and kit characterized by containing novel penicillin derivative or salt thereof and 1 or more compounds selected from beta-lactamase inhibitory compound and antibacterial compound or salt thereof | 富士胶片株式会社 | 2022-05-24 | — | — | CN | disclosed |
| EP-3693374-B1 | NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUND OR SALT, AND APPLICATION THEREOF | FUJIFILM CORP (JP) | 2022-01-26 | — | — | EP | disclosed |
| EP-3778609-B1 | PENAM DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | FUJIFILM CORP (JP) | 2022-01-26 | — | — | EP | disclosed |
| EP-3778609-B1 | PENAM DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | FUJIFILM CORP (JP) | 2022-01-26 | — | — | EP | disclosed |
| US-11208421-B2 | 2-carboxypenam compound or salt thereof, pharmaceutical composition containing novel 2-carboxypenam compound or salt thereof, and applications thereof | FUJIFILM CORPORATION (JP) | 2021-12-28 | — | — | US | disclosed |
| US-20210024543-A1 | NOVEL PENAM DERIVATIVE OR SALT THEREOF, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS THEREOF | FUJIFILM CORPORATION (JP) | 2021-01-28 | — | — | US | disclosed |
| CN-111954673-A | Novel penam derivative or salt thereof, pharmaceutical composition, and use thereof | 富士胶片株式会社 | 2020-11-17 | — | — | CN | disclosed |
| EP-3693374-A1 | NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUND OR SALT, AND APPLICATION THEREOF | Fujifilm Corporation (JP) | 2020-08-12 | — | — | EP | disclosed |
| US-20200239495-A1 | NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, AND APPLICATIONS THEREOF | FUJIFILM CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |
| WO-2019194306-A1 | NOVEL PENAM DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | 富士フイルム株式会社 | 2019-10-10 | — | — | WO | disclosed |
| WO-2019194306-A1 | NOVEL PENAM DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | 富士フイルム株式会社 | 2019-10-10 | — | — | WO | disclosed |
| WO-2019070052-A1 | NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUND OR SALT, AND APPLICATION THEREOF | 富士フイルム株式会社 | 2019-04-11 | — | — | WO | disclosed |
| US-20170281532-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2017-10-05 | — | — | US | disclosed |
| US-20150299223-A1 | 2-SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LTD (GB) | 2015-10-22 | — | — | US | disclosed |
| WO-2014068388-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2014-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11208421-B2 | 2-carboxypenam compound or salt thereof, pharmaceutical composition containing novel 2-carboxypenam compound or salt thereof, and applications thereof | CFTR, SLC11A2, SLC20A1 | POLB 2010/4885NPC1 2552/4885RAB9A 2188/4885 |
| US-20200239495-A1 | NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, AND APPLICATIONS THEREOF | CFTR, SLC11A2, SLC20A1 | POLB 2022/4885NPC1 2595/4885RAB9A 2021/4885 |
| US-20220241249-A1 | PHARMACEUTICAL COMPOSITION AND KIT CONTAINING NOVEL PENAM DERIVATIVE OR SALT THEREOF AND ONE OR MORE COMPOUNDS SELECTED FROM beta-LACTAMASE INHIBITORY COMPOUND AND ANTIBACTERIAL COMPOUND OR SALTS THEREOF | KIT, TPSAB1, MGAM | POLB 208/4885NPC1 3389/4885RAB9A 638/4885 |
| US-20170281532-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | CEP170, CES2, CMBL | POLB 655/4885NPC1 864/4885RAB9A 1873/4885 |
| US-20210024543-A1 | NOVEL PENAM DERIVATIVE OR SALT THEREOF, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS THEREOF | CFTR, SLC11A2, SLC20A1 | POLB 1056/4885NPC1 2668/4885RAB9A 757/4885 |
| US-12286440-B2 | Penam derivative or salt thereof, pharmaceutical composition, and applications thereof | CFTR, SLC11A2, REN | POLB 780/4885NPC1 2965/4885RAB9A 976/4885 |
| US-20150299223-A1 | 2-SUBSTITUTED CEPHEM COMPOUNDS | CEP170, ABL1, CEPT1 | POLB 840/4885NPC1 884/4885RAB9A 3113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.