Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | CA1 | P00915 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945452 | 0.84 | LMNA (0.62) | ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL392625 | 0.81 | ALDH1A1 (0.82) | ALDH1A1RAB9ANPC1LMNACA1 | |
| SCHEMBL5861356 | 0.79 | ALDH1A1 (1.00) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL6962946 | 0.79 | ALDH1A1 (0.58) | ALDH1A1RAB9ANPC1LMNACA1 | |
| SCHEMBL28992287 | 0.79 | ERCC1 (0.68) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL25046059 | 0.79 | ALDH1A1 (0.65) | ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL4717861 | 0.79 | CA12 (0.71) | ALDH1A1RAB9ANPC1LMNACA1 | |
| SCHEMBL28992212 | 0.79 | ALDH1A1 (1.00) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL28923083 | 0.78 | LMNA (0.55) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL14662131 | 0.78 | LMNA (0.52) | ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307017-A1 | COMPOUNDS WHICH CAN BE USED FOR THE TREATMENT OF CANCERS | Cytomics Systems (FR) | 2011-04-13 | — | — | EP | disclosed |