SCHEMBL15699343

SCHEMBL15699343

CC(C)(C(=O)OC1CCCO1)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.31
KMT2A Q03164 1/20 0.30
PDK1 Q15118 1/20 0.30
PDK2 Q15119 1/20 0.30
PDK3 Q15120 1/20 0.30
PDK4 Q16654 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12553878 0.82 POLB (0.36) CFTRKMT2AALDH1A1
SCHEMBL15699342 0.82 KMT2A (0.33) KMT2AALDH1A1
SCHEMBL15697291 0.81 LMNA (0.33) CFTRKMT2AALDH1A1
SCHEMBL12587749 0.81 PDK1 (0.31) KMT2APDK1PDK2PDK3PDK4
SCHEMBL15699350 0.81 MEN1 (0.34) KMT2APDK1PDK2PDK3PDK4
SCHEMBL12378376 0.81 MEN1 (0.34) KMT2APDK1PDK2PDK3PDK4
SCHEMBL20171541 0.81 MEN1 (0.34) KMT2A
SCHEMBL10098332 0.79 KMT2A (0.32) KMT2AALDH1A1
SCHEMBL26650279 0.77 KMT2A (0.34) KMT2AALDH1A1
SCHEMBL15697297 0.77 MEN1 (0.35) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9310682-B2 Positive-type resist composition CENTRAL GLASS COMPANY, LIMITED (JP) 2016-04-12 US disclosed
US-20140134542-A1 Positive-Type Resist Composition CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-15 US disclosed