Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.46 |
| ▸ | NPC1 | O15118 | 9/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15701057 | 0.90 | CASP3 (0.45) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL15701165 | 0.88 | ACP1 (0.46) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL19446717 | 0.88 | RAB9A (0.52) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL15701244 | 0.87 | CYP2C9 (0.49) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL15701145 | 0.85 | PSEN1 (0.46) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL15701026 | 0.85 | RAB9A (0.48) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL15701278 | 0.84 | CASP3 (0.50) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL15701115 | 0.84 | MAPT (0.51) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL15701087 | 0.84 | CYP2C9 (0.51) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL15701093 | 0.84 | CYP2C9 (0.51) | RAB9ANPC1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014070979-A1 | INHIBITORS OF CYTOMEGALOVIRUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-08 | — | — | WO | disclosed |