Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 11/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15701013 | 0.89 | CSNK1D (0.66) | MAPTL3MBTL1DYRK2CSNK1D | |
| SCHEMBL15701156 | 0.87 | RIPK1 (0.49) | MAPTL3MBTL1DYRK2CSNK1DDYRK1A | |
| SCHEMBL15701151 | 0.86 | CSNK1D (0.57) | MAPTDYRK2CSNK1DDYRK1ARAB9A | |
| SCHEMBL15701111 | 0.85 | CSNK1D (0.69) | DYRK2CSNK1D | |
| SCHEMBL15701166 | 0.84 | RAB9A (0.46) | MAPTCSNK1DRAB9ANPC1CASP3 | |
| SCHEMBL15701230 | 0.83 | DYRK2 (0.50) | MAPTL3MBTL1DYRK2CSNK1DDYRK1A | |
| SCHEMBL15701138 | 0.83 | WNT3A (0.58) | MAPTL3MBTL1CSNK1DRAB9ANPC1 | |
| SCHEMBL15701287 | 0.82 | LMNA (0.65) | MAPTCSNK1DSMN1; SMN2POLBKDM4E | |
| SCHEMBL15701153 | 0.82 | CSNK1D (0.61) | MAPTDYRK2CSNK1DRAB9ASMN1; SMN2 | |
| SCHEMBL17148444 | 0.79 | CSNK1D (0.50) | MAPTCSNK1DRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014070979-A1 | INHIBITORS OF CYTOMEGALOVIRUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-08 | — | — | WO | disclosed |