Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154356 | 0.98 | CA1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL889796 | 0.86 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL30788459 | 0.81 | TOP1 (0.40) | CA1CA2CA7CA9CA12 | |
| SCHEMBL2154131 | 0.79 | KCNH2 (0.32) | ALDH1A1TDP1KDM4E | |
| SCHEMBL3791862 | 0.78 | CA1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL29078208 | 0.78 | CA1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL2153580 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TDP1L3MBTL1POLBGAA | |
| SCHEMBL2153721 | 0.78 | IRAK4 (0.39) | ALDH1A1ADRA2BTDP1LMNAKDM4E | |
| SCHEMBL56425 | 0.78 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL30992110 | 0.78 | CA1 (0.50) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9707553-B2 | P-chirogenic organophosphorus compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-07-18 | — | — | US | disclosed |
| EP-3150613-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-04-05 | — | — | EP | disclosed |
| EP-2731956-B1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | CENTRE NAT RECH SCIENT (FR) | 2016-11-09 | — | — | EP | disclosed |
| US-20160023199-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | SYNTHELOR SAS (FR) | 2016-01-28 | — | — | US | disclosed |
| US-9186661-B2 | P-chirogenic organophosphorus compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-11-17 | — | — | US | disclosed |
| US-20140142325-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS) (FR) | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160023199-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | ACHE, PTMS, DDT | CA1 102/4885CA2 27/4885CA7 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.