SCHEMBL2154356

SCHEMBL2154356

COc1ccccc1P(Cl)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
CA12 O43570 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA4 P22748 2/20 0.46
ALDH1A1 P00352 5/20 0.39
TDP1 Q9NUW8 2/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
ADRA2B P18089 1/20 0.39
PTGS1 P23219 1/20 0.39
HTT P42858 2/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
LMNA P02545 2/20 0.37
ENPP2 Q13822 1/20 0.36
TRPA1 O75762 1/20 0.36
NFE2L2 Q16236 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15711151 0.98 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL889796 0.87 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL30788459 0.83 TOP1 (0.40) CA1CA2CA7CA9CA12
SCHEMBL2154131 0.81 KCNH2 (0.32) ALDH1A1TDP1KDM4EHSD17B10
SCHEMBL29078208 0.80 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL2153580 0.79 ALDH1A1 (0.44) ALDH1A1TDP1L3MBTL1POLBHPGD
SCHEMBL2153721 0.79 IRAK4 (0.39) ALDH1A1TDP1ADRA2BLMNAKDM4E
SCHEMBL476857 0.79 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL56425 0.79 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL30992110 0.79 CA1 (0.50) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000002890-A1 HYDROFORMYLATION PROCESS NESTE CHEMICALS OY (FI) 2000-01-20 WO claimed
CN-111018923-B Carbohydrate monophosphines, method for the production and use thereof 东莞市均成高新材料有限公司 2024-04-19 CN disclosed
EP-2994445-B1 OLIGOMERISATION OF ETHYLENE TO MIXTURES OF 1-HEXENE AND 1-OCTENE SASOL TECH PTY LTD (ZA) 2023-05-24 EP disclosed
EP-2994445-B1 OLIGOMERISATION OF ETHYLENE TO MIXTURES OF 1-HEXENE AND 1-OCTENE SASOL TECH PTY LTD (ZA) 2023-05-24 EP disclosed
EP-2994444-B1 OLIGOMERISATION OF ETHYLENE TO MIXTURES OF 1-HEXENE AND 1-OCTENE SASOL TECH PTY LTD (ZA) 2023-04-12 EP disclosed
EP-2994444-B1 OLIGOMERISATION OF ETHYLENE TO MIXTURES OF 1-HEXENE AND 1-OCTENE SASOL TECH PTY LTD (ZA) 2023-04-12 EP disclosed
CN-111018923-A Carbohydrate monophosphines, process for their preparation and their use 东莞市均成高新材料有限公司 2020-04-17 CN disclosed
EP-3184171-B1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-03-20 EP disclosed
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-12-04 US disclosed
US-9962689-B2 Phosphinyl formamidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-05-08 US disclosed
EP-2106402-A1 METHODS FOR OLIGOMERIZING OLEFINS WITH CHROMIUM PYRIDINE PHOSPHINO CATALYSTS ExxonMobil Chemical Patents Inc. (US) 2009-10-07 EP disclosed
US-20080188633-A1 Methods For Oligomerizing Olefins With Chromium Pyridine Phosphino Catalysts SYMYX TECHNOLOGIES, INC. 2008-08-07 US disclosed
US-20080188633-A1 Methods For Oligomerizing Olefins With Chromium Pyridine Phosphino Catalysts SYMYX TECHNOLOGIES, INC. 2008-08-07 US disclosed
US-20080188633-A1 Methods For Oligomerizing Olefins With Chromium Pyridine Phosphino Catalysts SYMYX TECHNOLOGIES, INC. 2008-08-07 US disclosed
WO-2008085653-A1 METHODS FOR OLIGOMERIZING OLEFINS WITH CHROMIUM PYRIDINE PHOSPHINO CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-07-17 WO disclosed
WO-2008085653-A1 METHODS FOR OLIGOMERIZING OLEFINS WITH CHROMIUM PYRIDINE PHOSPHINO CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-07-17 WO disclosed
US-20080058486-A1 Phosphine Ligand-Metal Compositions, Complexes, and Catalysts For Ethylene Trimerizations SYMYX TECHNOLOGIES INC. 2008-03-06 US disclosed
US-20080058486-A1 Phosphine Ligand-Metal Compositions, Complexes, and Catalysts For Ethylene Trimerizations SYMYX TECHNOLOGIES INC. 2008-03-06 US disclosed
US-20080058486-A1 Phosphine Ligand-Metal Compositions, Complexes, and Catalysts For Ethylene Trimerizations SYMYX TECHNOLOGIES INC. 2008-03-06 US disclosed
WO-2000002890-A1 HYDROFORMYLATION PROCESS NESTE CHEMICALS OY (FI) 2000-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins NIT2, NCLN, NPM1 CA1 676/4885CA2 475/4885CA7 1701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.