Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18315874 | 0.84 | APP (0.47) | PDK2PDCD1CD274IDH1MEN1 | |
| SCHEMBL12737112 | 0.84 | TOP1 (0.46) | PDK2MEN1KMT2ACA1CA2 | |
| SCHEMBL16572260 | 0.80 | PDCD1 (0.47) | PDK2PDCD1CD274IDH1MEN1 | |
| SCHEMBL12808219 | 0.80 | MEN1 (0.44) | PDK2PDCD1CD274IDH1MEN1 | |
| SCHEMBL22227385 | 0.78 | GABRA1 (0.42) | PDK2MEN1KMT2ACA1CA2 | |
| SCHEMBL14124477 | 0.76 | PDCD1 (0.51) | PDCD1CD274MEN1KMT2ACA1 | |
| SCHEMBL31134187 | 0.75 | ERN1 (0.50) | PDCD1CD274MEN1KMT2ACA1 | |
| SCHEMBL14605308 | 0.75 | MCL1 (0.35) | PDCD1CD274ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL14134329 | 0.73 | CD274 (0.40) | PDCD1CD274MEN1KMT2ACA1 | |
| SCHEMBL12203538 | 0.73 | APP (0.48) | CA1CA2CA7CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816112-B2 | Process for making novel chiral phosphorus ligands | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-08-26 | — | — | US | disclosed |
| US-20140135506-A1 | PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135506-A1 | PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS | PHOSPHO1, INPP5B, PLCG2 | PDK2 1824/4885PDCD1 1298/4885CD274 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.