Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 5/20 | 0.36 |
| ▸ | METAP1 | P53582 | 4/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15712953 | 0.82 | AKR1C4 (0.39) | KAT6ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1365903 | 0.80 | CXCR1 (0.35) | NPC1RAB9ACTSLCTSBCTSS | |
| SCHEMBL1362965 | 0.79 | AR (0.41) | NPC1ALDH1A1RAB9AMETAP2METAP1 | |
| SCHEMBL1364488 | 0.79 | AR (0.41) | NPC1ALDH1A1RAB9AMETAP2METAP1 | |
| SCHEMBL1364617 | 0.79 | METAP2 (0.43) | ALDH1A1METAP2METAP1 | |
| SCHEMBL12306450 | 0.78 | L3MBTL1 (0.35) | NPC1RAB9ASMN1; SMN2CTSLCTSB | |
| SCHEMBL1365002 | 0.78 | CXCR1 (0.38) | NPC1ALDH1A1RAB9ASMN1; SMN2CTSV | |
| SCHEMBL12140312 | 0.78 | CXCR1 (0.38) | NPC1ALDH1A1RAB9ASMN1; SMN2CTSV | |
| SCHEMBL12140344 | 0.78 | CXCR1 (0.38) | NPC1ALDH1A1RAB9ASMN1; SMN2CTSV | |
| SCHEMBL12140241 | 0.78 | CTSL (0.34) | ALDH1A1SMN1; SMN2CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260028-B1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH INC (US) | 2014-05-07 | — | — | EP | disclosed |