SCHEMBL15712971

SCHEMBL15712971

Cc1ccc(C2=Cc3c(cc(C)c(C)c3-c3ccccc3)C2)o1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
PKM P14618 2/20 0.32
HPGD P15428 2/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALOX12 P18054 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18393559 0.95 PTGS1 (0.37) PTGS1PTGS2ADORA2AADORA1MEN1
SCHEMBL18393554 0.87
SCHEMBL28662372 0.87 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL18393491 0.85 MEN1 (0.30) MEN1KMT2A
SCHEMBL17060058 0.85
SCHEMBL18393621 0.85
SCHEMBL2239872 0.84 PTGS1 (0.42) PTGS1PTGS2ADORA2AADORA1MEN1
SCHEMBL29459245 0.83 PTGS1 (0.40) PTGS1PTGS2ADORA2AADORA1MEN1
SCHEMBL2236714 0.82 PTGS1 (0.40) PTGS1PTGS2ADORA2AADORA1MEN1
SCHEMBL17771935 0.78 ALDH1A1 (0.38) PTGS1PTGS2ADORA2AADORA1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483670-B Metallocene complex and process for producing olefin polymer 日本聚丙烯株式会社 2021-11-30 CN disclosed
CN-110483670-A The method of metallocene complex and production olefin polymer JAPAN POLYPROPYLENE CORP 2019-11-22 CN disclosed
CN-106132975-B Metallocene complex and process for producing olefin polymer 日本聚丙烯株式会社 2019-11-08 CN disclosed
EP-3121187-B1 METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER JAPAN POLYPROPYLENE CORP (JP) 2018-10-10 EP disclosed
US-9963522-B2 Metallocene complex and method for producing olefin polymer JAPAN POLYPROPYLENE CORPORATION (JP) 2018-05-08 US disclosed
US-9963522-B2 Metallocene complex and method for producing olefin polymer JAPAN POLYPROPYLENE CORPORATION (JP) 2018-05-08 US disclosed
US-9963522-B2 Metallocene complex and method for producing olefin polymer JAPAN POLYPROPYLENE CORPORATION (JP) 2018-05-08 US disclosed
US-9902749-B2 Metallocene complex and olefin polymerization method JAPAN POLYPROPYLENE CORPORATION (JP) 2018-02-27 US disclosed
US-9902749-B2 Metallocene complex and olefin polymerization method JAPAN POLYPROPYLENE CORPORATION (JP) 2018-02-27 US disclosed
US-9902749-B2 Metallocene complex and olefin polymerization method JAPAN POLYPROPYLENE CORPORATION (JP) 2018-02-27 US disclosed
CN-106132975-A metallocene complex and process for producing olefin polymer 日本聚丙烯株式会社 2016-11-16 CN disclosed
EP-2915816-B1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD JAPAN POLYPROPYLENE CORP (JP) 2016-05-25 EP disclosed
WO-2015141675-A1 METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER 日本ポリプロ株式会社 2015-09-24 WO disclosed
US-20150266914-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD JAPAN POLYPROPYLENE CORPORATION (JP) 2015-09-24 US disclosed
US-20150266914-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD JAPAN POLYPROPYLENE CORPORATION (JP) 2015-09-24 US disclosed
US-20150266914-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD JAPAN POLYPROPYLENE CORPORATION (JP) 2015-09-24 US disclosed
EP-2915816-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD Japan Polypropylene Corporation (JP) 2015-09-09 EP disclosed
EP-2915816-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD Japan Polypropylene Corporation (JP) 2015-09-09 EP disclosed
CN-104781270-A Metallocene complexes and olefin polymerization process JAPAN POLYPROPYLENE CORP 2015-07-15 CN disclosed
WO-2014069391-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD 日本ポリプロ株式会社 (JP) 2014-05-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150266914-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD POR, OPRM1, ALOX12 PTGS1 201/4885PTGS2 182/4885ADORA2A 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.