Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ENTPD1 | P49961 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15704019 | 1.00 | TRPM2 (0.60) | TRPM2POLBENTPD1LMNATP53 | |
| SCHEMBL7644549 | 0.87 | TRPM2 (0.65) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL30134675 | 0.86 | TRPM2 (0.64) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL12932270 | 0.86 | TRPM2 (0.64) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL7648504 | 0.86 | TRPM2 (0.64) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL1063721 | 0.86 | TRPM2 (0.64) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL16060166 | 0.85 | TRPM2 (0.53) | TRPM2ENTPD1LMNATP53HBB | |
| SCHEMBL15245119 | 0.85 | LMNA (0.69) | ENTPD1LMNATP53HBBSMN1; SMN2 | |
| SCHEMBL15456809 | 0.85 | LMNA (0.69) | ENTPD1LMNATP53HBBSMN1; SMN2 | |
| SCHEMBL29413068 | 0.85 | LMNA (0.69) | ENTPD1LMNATP53HBBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275672-A1 | CHEMICALLY MODIFIED LIGASE COFACTORS, DONORS AND ACCEPTORS | TRILINK BIOTECHNOLOGIES, INC. (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170275672-A1 | CHEMICALLY MODIFIED LIGASE COFACTORS, DONORS AND ACCEPTORS | TRILINK BIOTECHNOLOGIES, INC. (US) | 2017-09-28 | — | — | US | disclosed |
| US-9631227-B2 | Chemically modified ligase cofactors, donors and acceptors | TRILINK BIOTECHNOLOGIES, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-9631227-B2 | Chemically modified ligase cofactors, donors and acceptors | TRILINK BIOTECHNOLOGIES, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-20140323354-A1 | Chemically Modified Ligase Cofactors, Donors and Acceptors | TRILINK BIOTECHNOLOGIES, INC. (US) | 2014-10-30 | — | — | US | disclosed |
| US-20140323354-A1 | Chemically Modified Ligase Cofactors, Donors and Acceptors | TRILINK BIOTECHNOLOGIES, INC. (US) | 2014-10-30 | — | — | US | disclosed |
| WO-2014144979-A1 | CHEMICALLY MODIFIED LIGASE COFACTORS, DONORS AND ACCEPTORS | TRILINK BIOTECHNOLOGIES, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| US-8728725-B2 | Chemically modified ligase cofactors, donors and acceptors | TRILINK BIOTECHNOLOGIES (US) | 2014-05-20 | — | — | US | disclosed |
| US-8728725-B2 | Chemically modified ligase cofactors, donors and acceptors | TRILINK BIOTECHNOLOGIES (US) | 2014-05-20 | — | — | US | disclosed |
| US-20110008788-A1 | CHEMICALLY MODIFIED LIGASE COFACTORS, DONORS AND ACCEPTORS | TriLink Bio Technologies | 2011-01-13 | — | — | US | disclosed |
| US-20110008788-A1 | CHEMICALLY MODIFIED LIGASE COFACTORS, DONORS AND ACCEPTORS | TriLink Bio Technologies | 2011-01-13 | — | — | US | disclosed |
| WO-2011005762-A1 | CHEMICALLY MODIFIED LIGASE COFACTORS, DONORS AND ACCEPTORS | TRILINK BIOTECHNOLOGIES (US) | 2011-01-13 | — | — | WO | disclosed |