Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ENTPD1 | P49961 | 3/20 | 0.55 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.52 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16208893 | 0.92 | POLB (0.57) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL16208897 | 0.92 | POLB (0.57) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL7644549 | 0.90 | TRPM2 (0.65) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL12932270 | 0.90 | TRPM2 (0.64) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL1063721 | 0.90 | TRPM2 (0.64) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL30134675 | 0.90 | TRPM2 (0.64) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL2232893 | 0.86 | TRPM2 (0.61) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL15704019 | 0.86 | TRPM2 (0.60) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL1509270 | 0.86 | TRPM2 (0.60) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL15715797 | 0.86 | TRPM2 (0.60) | TRPM2POLBENTPD1ENPP1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140170689-A1 | Modified Diguanylate Cyclase-Phosphodiesterase and Method for Enzymatic Production of Cyclic-diGMP | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-06-19 | — | — | US | claimed |
| WO-2002004686-A2 | DETECTING METHYLATED CYTOSINE IN POLYNUCLEOTIDES | EPIGENX PHARMACEUTICAL, INC. (US) | 2002-01-17 | — | — | WO | claimed |
| US-20140170689-A1 | Modified Diguanylate Cyclase-Phosphodiesterase and Method for Enzymatic Production of Cyclic-diGMP | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-06-19 | — | — | US | disclosed |
| WO-2002004686-A2 | DETECTING METHYLATED CYTOSINE IN POLYNUCLEOTIDES | EPIGENX PHARMACEUTICAL, INC. (US) | 2002-01-17 | — | — | WO | disclosed |