Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15716418 | 0.92 | PTPN1 (0.51) | ALDH1A1USP2TSHRHSD17B10LMNA | |
| SCHEMBL10592075 | 0.79 | SRD5A2 (0.58) | ALDH1A1USP2TSHRHSD17B10LMNA | |
| SCHEMBL6595625 | 0.71 | SRD5A2 (0.77) | ALDH1A1USP2TSHRHSD17B10LMNA | |
| SCHEMBL7879867 | 0.71 | SRD5A2 (0.51) | ALDH1A1USP2TSHRHSD17B10LMNA | |
| SCHEMBL7157950 | 0.71 | SRD5A1 (0.51) | ALDH1A1USP2TSHRHSD17B10LMNA | |
| SCHEMBL2338199 | 0.71 | HPGD (0.76) | ALDH1A1USP2TSHRHSD17B10LMNA | |
| SCHEMBL187450 | 0.70 | SRD5A2 (0.64) | ALDH1A1USP2TSHRHSD17B10LMNA | |
| SCHEMBL7168633 | 0.70 | SRD5A2 (0.56) | ALDH1A1USP2TSHRHSD17B10LMNA | |
| SCHEMBL8323967 | 0.70 | SRD5A2 (0.50) | ALDH1A1USP2TSHRHSD17B10LMNA | |
| SCHEMBL7159304 | 0.70 | SRD5A2 (0.82) | ALDH1A1HSD17B10HPGDSRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2920157-A1 | DI-MACROCYCLES | Lumiphore, Inc. (US) | 2015-09-23 | — | — | EP | disclosed |
| WO-2014078690-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2014-05-22 | — | — | WO | disclosed |