Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15716144 | 0.92 | ALDH1A1 (0.49) | PTPN1USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL10592075 | 0.80 | SRD5A2 (0.58) | PTPN1USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7879867 | 0.75 | SRD5A2 (0.51) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL7157950 | 0.74 | SRD5A1 (0.51) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL7174106 | 0.73 | SRD5A2 (0.50) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL8323967 | 0.73 | SRD5A2 (0.50) | PTPN1USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL6595625 | 0.72 | SRD5A2 (0.77) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL20605051 | 0.72 | SRD5A2 (0.49) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL20597207 | 0.72 | SRD5A2 (0.49) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL20604836 | 0.72 | SRD5A2 (0.49) | USP2ALDH1A1TSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2920157-A1 | DI-MACROCYCLES | Lumiphore, Inc. (US) | 2015-09-23 | — | — | EP | disclosed |
| WO-2014078690-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2014-05-22 | — | — | WO | disclosed |