Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.58 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532625 | 0.81 | SRD5A2 (0.55) | SRD5A2SRD5A1ALDH1A1HSD17B10HPGD | |
| SCHEMBL15716418 | 0.80 | PTPN1 (0.51) | SRD5A2SRD5A1ALDH1A1HSD17B10HPGD | |
| SCHEMBL15716144 | 0.79 | ALDH1A1 (0.49) | SRD5A2SRD5A1ALDH1A1HSD17B10HPGD | |
| SCHEMBL793724 | 0.79 | MEN1 (0.65) | SRD5A2HPGDKDM4EMEN1KMT2A | |
| SCHEMBL5555614 | 0.78 | PDE3B (0.48) | SRD5A2SRD5A1ALDH1A1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL514496 | 0.77 | MEN1 (0.63) | SRD5A2HPGDKDM4EMEN1KMT2A | |
| SCHEMBL14660694 | 0.77 | MEN1 (0.63) | SRD5A2HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10590979 | 0.76 | POLB (0.56) | SRD5A2SRD5A1ALDH1A1HSD17B10HPGD | |
| SCHEMBL2090373 | 0.74 | LMNA (0.52) | HPGDCYP1A2FOLH1PTPN1LMNA | |
| SCHEMBL7174812 | 0.74 | SRD5A2 (0.88) | SRD5A2SRD5A1ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336369-A1 | 3-Acylamino-1-[[[(substituted sulfonyl)amino]carbonyl]amino]2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1989-10-11 | — | — | EP | disclosed |