⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454 | 0.96 | — | — | |
| SCHEMBL27457813 | 0.96 | ALDH1A1 (0.44) | — | |
| SCHEMBL6295419 | 0.93 | — | — | |
| SCHEMBL30385793 | 0.93 | — | — | |
| Methane SCHEMBL27972515 | 0.93 | — | — | |
| SCHEMBL3949253 | 0.93 | — | — | |
| Urea SCHEMBL2148631 | 0.93 | ALDH1A1 (0.43) | — | |
| Ammonia Solution, Strong SCHEMBL17685472 | 0.93 | — | — | |
| Phosphine SCHEMBL21586379 | 0.93 | — | — | |
| Water SCHEMBL27176182 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885757-B1 | METHOD FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING AN X-RAY TUBE | ICAGEN LLC (US) | 2024-12-11 | — | — | EP | disclosed |
| US-11639941-B2 | Methods for measuring analyte transport across barriers using X-ray fluorescence | ICAGEN, LLC (US) | 2023-05-02 | — | — | US | disclosed |
| EP-3885757-A1 | METHOD FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING AN X-RAY TUBE | Icagen, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| EP-3381359-B1 | METHOD FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING AN X-RAY TUBE | ICAGEN INC (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3381359-A1 | METHOD FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING AN X-RAY TUBE | Icagen, Inc. (US) | 2018-10-03 | — | — | EP | disclosed |
| US-10082511-B2 | Methods for measuring analyte transport across barriers using X-ray fluorescence | ICAGEN, INC. (US) | 2018-09-25 | — | — | US | disclosed |
| EP-2306897-B1 | METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS | ICAGEN INC (US) | 2018-05-30 | — | — | EP | disclosed |
| US-20170045530-A1 | METHODS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING X-RAY FLUORESCENCE | ICAGEN, INC. (US) | 2017-02-16 | — | — | US | disclosed |
| US-9506931-B2 | Method for measuring analyte transport across cell membranes using X-ray fluorescence | ICAGEN, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20150198615-A1 | METHODS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS USING X-RAY FLUORESCENCE | XRPRO SCIENCES, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| US-20130236887-A1 | Method and Apparatus for Measuring Analyte Transport Across Barriers | CALDERA PHARMACEUTICALS, INC. (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130172374-A1 | SOLID COMPOSITION FOR CONTROLLED RELEASE OF IONIZABLE ACTIVE AGENTS WITH POOR AQUEOUS SOLUBILITY AT LOW PH AND METHODS OF USE THEREOF | PORTOLA PHARMACEUTICALS, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8431357-B2 | Method and apparatus for measuring analyte transport across barriers using x-ray fluorescence | CALDERA PHARMACEUTICALS, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| CN-102905517-A | Gene switch compositions and methods of use | PIONEER HI BRED INT | 2013-01-30 | — | — | CN | disclosed |
| US-20120129876-A1 | [4-(6-FLUORO-7-METHYLAMINO-2,4-DIOXO-1,4-DIHYDRO-2H-QUINAZOLIN-3-YL)-PHENYL]-5-CHLORO-THIOPHEN-2-YL-SULFONYLUREA SALTS, FORMS AND METHODS RELATED THERETO | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-05-24 | — | — | US | disclosed |
| EP-2306897-A1 | METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS | Caldera Pharmaceuticals, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| US-20100151019-A1 | SOLID COMPOSITION FOR CONTROLLED RELEASE OF IONIZABLE ACTIVE AGENTS WITH POOR AQUEOUS SOLUBILITY AT LOW pH AND METHODS OF USE THEREOF | PORTOLA PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-20100003697-A1 | Method and Apparatus for Measuring Analyte Transport Across Barriers | CALDERA PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | US | disclosed |
| WO-2010003017-A1 | METHOD AND APPARATUS FOR MEASURING ANALYTE TRANSPORT ACROSS BARRIERS | CALDERA PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |
| US-20090042916-A1 | [4-(6-FLUORO-7-METHYLAMINO-2,4-DIOXO-1,4-DIHYDRO-2H-QUINAZOLIN-3-YL)-PHENYL]-5-CHLORO-THIOPHEN-2-YL-SULFONYLUREA SALTS, FORMS AND METHODS RELATED THERETO | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-02-12 | — | — | US | disclosed |