⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454 | 0.96 | — | — | |
| SCHEMBL27457813 | 0.96 | ALDH1A1 (0.44) | — | |
| SCHEMBL30385793 | 0.93 | — | — | |
| Phosphine SCHEMBL21586379 | 0.93 | — | — | |
| Hydrogen Sulfide SCHEMBL28213513 | 0.93 | — | — | |
| Urea SCHEMBL2148631 | 0.93 | ALDH1A1 (0.43) | — | |
| SCHEMBL6295419 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL17685472 | 0.93 | — | — | |
| SCHEMBL1571702 | 0.93 | — | — | |
| Water SCHEMBL27176182 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806513-B | Oil-based penetration-promoting spreading synergistic additive and application thereof in chemical thinning | 中国农业大学 | 2023-05-02 | — | — | CN | claimed |
| CN-112239429-A | Discovery and application of novel structure and novel function of sulfonylurea herbicides with controllable soil degradation speed | 南开大学 | 2021-01-19 | — | — | CN | claimed |
| CN-115806513-B | Oil-based penetration-promoting spreading synergistic additive and application thereof in chemical thinning | 中国农业大学 | 2023-05-02 | — | — | CN | disclosed |
| EP-2076510-A2 | [4-(6-FLUORO-7-METHYLAMINO-2,4-DIOXO-1,4-DIHYDRO-2H-QUINAZOLIN-3-YL)-PHENYL]-5-CHLORO-THIOPHEN-2-YL-SULFONYLUREA SALTS, IN DIFFERENT CRYSTALLINE FORMS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND FORMULATIONS THEREOF, FOR THE TREATMENT OF THROMBOSIS AND TROMBOSIS RELATED CONDITIONS | Portola Pharmaceuticals, Inc. (US) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008137809-A2 | [4-(6-FLUORO-7-METHYLAMINO-2,4-DIOXO-1,4-DIHYDRO-2H-QUINAZOLIN-3-YL)-PHENYL] -5-CHLORO-THIOPHEN-2-YL-SULFONYLUREA SALTS, IN DIFFERENT CRYSTALLINE FORMS, PHARMACEUTICAL COMPOSITIONS THEREOF | PORTOLA PHARMACEUTICALS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |