Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30980395 | 0.84 | AOC2 (0.50) | NAMPTNTRK1ADRA1AHTR1ADRD2 | |
| SCHEMBL2176055 | 0.81 | ESR1 (0.46) | NAMPTNTRK1ADRA1AHTR1ADRD2 | |
| SCHEMBL3642134 | 0.81 | JMJD6 (0.44) | NAMPTADRA1AHTR1ADRD2DRD1 | |
| SCHEMBL3081703 | 0.80 | ESR1 (0.47) | NAMPTADRA1AHTR1ADRD2DRD1 | |
| SCHEMBL15718194 | 0.79 | RAB9A (0.51) | NAMPTADRA1AHTR1ADRD2DRD1 | |
| SCHEMBL3089155 | 0.78 | ESR1 (0.43) | NAMPTNTRK1ADRA1AHTR1ADRD2 | |
| SCHEMBL27906136 | 0.77 | ESR1 (0.52) | NAMPTNTRK1ADRA1AHTR1ADRD2 | |
| SCHEMBL27326899 | 0.77 | ALDH1A1 (0.44) | HDAC8HDAC6PLK1THRBHDAC2 | |
| SCHEMBL31288941 | 0.77 | MAPK1 (0.52) | NAMPTNTRK1TDP1 | |
| SCHEMBL31205259 | 0.77 | ESR1 (0.45) | NAMPTNTRK1ADRA1AHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695248-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024213663-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-10-17 | — | — | WO | disclosed |
| EP-2925757-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | Novartis AG (CH) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014078802-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | IRM LLC (BM) | 2014-05-22 | — | — | WO | disclosed |