Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 3/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130477 | 0.97 | TSHR (0.52) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL17326863 | 0.79 | TSHR (0.52) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL2426552 | 0.75 | TSHR (0.50) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL14470743 | 0.74 | HSD17B10 (0.37) | TSHRHSD17B10TDP1CA1CA2 | |
| Succinic Acid SCHEMBL7784488 | 0.72 | LMNA (0.64) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL342096 | 0.72 | TSHR (0.93) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| E388 SCHEMBL341724 | 0.69 | LMNA (0.93) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| Succinic Acid SCHEMBL285597 | 0.68 | LMNA (0.69) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL95982 | 0.68 | TSHR (1.00) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL17634264 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2920296-A1 | CELL CULTURE MED | Merck Patent GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| WO-2014075807-A1 | CELL CULTURE MED | MERCK PATENT GMBH (DE) | 2014-05-22 | — | — | WO | disclosed |