SCHEMBL2426552

SCHEMBL2426552

CS(=O)(=O)SCCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
TRPA1 O75762 1/20 0.48
LMNA P02545 4/20 0.48
KMT2A Q03164 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
SLC6A4 P31645 1/20 0.44
HDAC3 O15379 3/20 0.40
HDAC1 Q13547 3/20 0.40
HDAC2 Q92769 3/20 0.40
HDAC8 Q9BY41 3/20 0.40
HDAC4 P56524 2/20 0.40
HDAC7 Q8WUI4 2/20 0.40
HDAC10 Q969S8 2/20 0.40
HDAC11 Q96DB2 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40
HDAC9 Q9UKV0 2/20 0.40
HDAC5 Q9UQL6 2/20 0.40
APEX1 P27695 1/20 0.40
ALKBH5 Q6P6C2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10495189 0.86 TSHR (0.50) TSHRTRPA1LMNAKMT2AHSD17B10
SCHEMBL3972649 0.84 LMNA (0.48) TSHRTRPA1LMNAKMT2AHSD17B10
SCHEMBL4861479 0.82 TSHR (0.50) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL10495218 0.82 TSHR (0.50) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL5479626 0.78 TRPA1 (0.52) TRPA1SLC6A4HDAC3HDAC1HDAC2
SCHEMBL11130477 0.77 TSHR (0.52) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL15719781 0.75 TSHR (0.50) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL4738894 0.75 TSHR (0.50) TSHRTRPA1LMNAKMT2AHSD17B10
SCHEMBL14651687 0.74 TRPA1 (0.67) TRPA1SLC6A4HDAC3HDAC1HDAC2
SCHEMBL30266795 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2170819-B1 PROSTAGLANDIN PHARMACEUTICAL COMPOSITIONS CTG PHARMA S R L (IT) 2011-09-21 EP claimed
US-20100168216-A1 PROSTAGLANDIN PHARMACEUTICAL COMPOSITIONS CTG PHARMA S.R.L. (IT) 2010-07-01 US claimed
EP-2170819-A1 PROSTAGLANDIN PHARMACEUTICAL COMPOSITIONS CTG Pharma S.r.l. (IT) 2010-04-07 EP claimed
WO-2009156466-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES CTG PHARMA S.R.L. (IT) 2009-12-30 WO claimed
WO-2009109501-A2 OCULAR PHARMACEUTICAL COMPOSITIONS CTG PHARMA S.R.L. (IT) 2009-09-11 WO claimed
WO-2009065926-A2 NEW ANTICANCER COMPOUNDS SULFIDRIS S.R.L. (IT) 2009-05-28 WO claimed
WO-2009037556-A1 NEW AGENTS FOR THE TREATMENT OF THE LOW URINARY TRACT DYSFUNCTIONS CTG PHARMA S.R.L. (IT) 2009-03-26 WO claimed
US-20090017003-A1 THIOSULFONATE ANTI-INFLAMMATORY AGENTS SULFIDRIS S.R.L. (IT) 2009-01-15 US claimed
WO-2008146105-A1 PROSTAGLANDIN PHARMACEUTICAL COMPOSITIONS CTG PHARMA S.R.L. (IT) 2008-12-04 WO claimed
WO-2008122356-A1 CARDIOVASCULAR AGENTS CTG PHARMA S.R.L. (IT) 2008-10-16 WO claimed
EP-1980559-A1 Cardiovascular agents CTG Pharma S.r.l. (IT) 2008-10-15 EP claimed
WO-2008077453-A1 5-FLUOROURACIL DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER SULFIDRIS, S.R.L. (IT) 2008-07-03 WO claimed
EP-1939186-A1 5-Fluorouracil derivatives and their use for the treatment of cancer Sulfidris S.r.l. (IT) 2008-07-02 EP claimed
WO-2007101606-A1 THIOSULFONATE ANTI-INFLAMMATORY AGENTS SULFIDRIS S.R.L. (IT) 2007-09-13 WO claimed
EP-1832575-A1 Anti-inflammatory agents Sulfidris S.r.l. (IT) 2007-09-12 EP claimed
US-20260049991-A1 SINGLE-MOLECULE PEPTIDE SEQUENCING USING GUANIDINYLATING AGENTS GLYPHIC BIOTECHNOLOGIES INC (US) 2026-02-19 US disclosed
EP-4655289-A1 SINGLE-MOLECULE PEPTIDE SEQUENCING USING GUANIDINYLATING AGENTS Glyphic Biotechnologies, Inc. (US) 2025-12-03 EP disclosed
EP-0234600-A1 Ligand/receptor pair-binding compounds THE UPJOHN COMPANY (US) 1987-09-02 EP disclosed
US-4614712-A Immunoassays with luciferase labeled ligands or receptors THE UPJOHN COMPANY (US) 1986-09-30 US disclosed
EP-0117693-A2 Enzyme-linked immunoassay, assay kits and pair-binding compounds THE UPJOHN COMPANY (US) 1984-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049991-A1 SINGLE-MOLECULE PEPTIDE SEQUENCING USING GUANIDINYLATING AGENTS CHAMP1, S100A11, TFIP11 TSHR 3021/4885TRPA1 4171/4885LMNA 949/4885
US-20100168216-A1 PROSTAGLANDIN PHARMACEUTICAL COMPOSITIONS PTGIS, PTGIR, PTGS1 TSHR 3087/4885TRPA1 495/4885LMNA 2646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.