Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.73 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.73 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | UBE2N | P61088 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.65 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PDE1A | P54750 | 1/20 | 0.54 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.54 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17750785 | 0.86 | LMNA (0.89) | SMN1; SMN2ADORA2BRXFP1HTTLMNA | |
| SCHEMBL1944405 | 0.84 | ADORA2B (1.00) | SMN1; SMN2ADORA2BRXFP1HTTLMNA | |
| SCHEMBL7118850 | 0.81 | BACE1 (0.49) | SMN1; SMN2ADORA2BRXFP1HTTLMNA | |
| SCHEMBL20561174 | 0.81 | LMNA (1.00) | SMN1; SMN2ADORA2BRXFP1HTTLMNA | |
| SCHEMBL20561098 | 0.81 | LMNA (0.80) | SMN1; SMN2ADORA2BRXFP1HTTLMNA | |
| SCHEMBL17772702 | 0.81 | SMN1; SMN2 (0.74) | SMN1; SMN2ADORA2BRXFP1HTTLMNA | |
| SCHEMBL20561381 | 0.80 | LMNA (0.79) | SMN1; SMN2ADORA2BRXFP1HTTLMNA | |
| SCHEMBL12604441 | 0.80 | RXFP1 (0.74) | SMN1; SMN2ADORA2BRXFP1HTTLMNA | |
| SCHEMBL20561099 | 0.80 | LMNA (0.78) | SMN1; SMN2ADORA2BRXFP1HTTLMNA | |
| SCHEMBL20561815 | 0.79 | ADORA2B (0.71) | SMN1; SMN2ADORA2BRXFP1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278951-B2 | Azolium and purinium salt anticancer and antimicrobial agents | THE UNIVERSITY OF AKRON (US) | 2016-03-08 | — | — | US | disclosed |
| US-9278951-B2 | Azolium and purinium salt anticancer and antimicrobial agents | THE UNIVERSITY OF AKRON (US) | 2016-03-08 | — | — | US | disclosed |
| US-20140142307-A1 | AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS | THE UNIVERSITY OF AKRON | 2014-05-22 | — | — | US | disclosed |
| US-20140142307-A1 | AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS | THE UNIVERSITY OF AKRON | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142307-A1 | AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS | PCNA, ITPA, MPI | SMN1; SMN2 3715/4885ADORA2B 3090/4885RXFP1 3987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.