Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15722884 | 0.95 | POLB (0.38) | POLBLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL15726742 | 0.73 | TP53 (0.33) | POLBLMNATP53ALDH1A1 | |
| SCHEMBL14005762 | 0.65 | ALDH1A1 (0.56) | POLBLMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL12284720 | 0.65 | HTT (0.55) | POLBLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL6463651 | 0.64 | KMT2A (0.72) | LMNATP53ALDH1A1TSHRRAB9A | |
| SCHEMBL16926205 | 0.64 | ALDH1A1 (0.59) | LMNAALDH1A1SMN1; SMN2MAPTCRHBP | |
| SCHEMBL4518402 | 0.63 | PLK1 (0.59) | LMNAALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL13868093 | 0.63 | LMNA (0.51) | LMNATP53ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13868094 | 0.63 | LMNA (0.51) | LMNATP53ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL19083031 | 0.62 | SMN1; SMN2 (0.46) | POLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140137734-A1 | CROSS-LINKED POLYIMIDE MEMBRANES FOR SEPARATIONS | UOP LLC (US) | 2014-05-22 | — | — | US | disclosed |