SCHEMBL15722952

SCHEMBL15722952

CCCCC/C=C/Oc1ccc(-c2ccc(CCC)cc2)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.36
LTA4H P09960 3/20 0.35
TNNC1 P63316 1/20 0.34
MPL P40238 3/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
HTR1A P08908 3/20 0.32
CNR1 P21554 3/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2E1 P05181 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX5 P09917 1/20 0.32
CYP2C8 P10632 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2A6 P11509 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2B6 P20813 1/20 0.32
CYP2C19 P33261 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15722953 0.99 RARB (0.38) RARBLTA4HTNNC1MPLGABRA1
SCHEMBL15722951 0.96 GABRA1 (0.35) RARBLTA4HTNNC1MPLGABRA1
SCHEMBL15722949 0.91 MPL (0.32) RARBMPLGABRA1GABRB2ALOX5
SCHEMBL15722950 0.87 GABRA1 (0.33) RARBMPLGABRA1GABRB2ALOX5
SCHEMBL15722912 0.83 MPL (0.33) RARBMPLGABRA1GABRB2ALOX5
SCHEMBL15722972 0.82 CTSS (0.45) LTA4HCNR1
SCHEMBL15722943 0.82 RARB (0.43) RARBMPLCYP3A4HSD11B1RARA
SCHEMBL15722946 0.81 RARB (0.44) RARBCYP3A4HSD11B1RARARARG
SCHEMBL15722945 0.81 RARB (0.44) RARBCYP3A4HSD11B1RARARARG
SCHEMBL15722944 0.81 RARB (0.44) RARBCYP3A4HSD11B1RARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9193907-B2 Liquid crystal compound having vinyloxy, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20140138582-A1 LIQUID CRYSTAL COMPOUND HAVING VINYLOXY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-22 US disclosed