SCHEMBL15722949

SCHEMBL15722949

CCC/C=C/Oc1ccc(-c2ccc(CCC)cc2)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MPL P40238 3/20 0.32
GABRA1 P14867 4/20 0.32
GABRB2 P47870 4/20 0.32
ALOX5 P09917 1/20 0.32
CTSL P07711 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
RARB P10826 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15722951 0.92 GABRA1 (0.35) MPLGABRA1GABRB2ALOX5CTSL
SCHEMBL15722952 0.91 RARB (0.36) MPLGABRA1GABRB2ALOX5RARB
SCHEMBL15722950 0.91 GABRA1 (0.33) MPLGABRA1GABRB2ALOX5CTSL
SCHEMBL15722953 0.90 RARB (0.38) MPLGABRA1GABRB2RARB
SCHEMBL15722912 0.86 MPL (0.33) MPLGABRA1GABRB2ALOX5CTSL
SCHEMBL15722994 0.83 CTSL (0.34) GABRA1GABRB2CTSLCTSSCTSK
SCHEMBL20273257 0.82 THRB (0.37) MPLGABRA1GABRB2ALOX5CTSL
SCHEMBL15722970 0.81 CTSS (0.48) CTSLCTSSCTSK
SCHEMBL15722942 0.79 MPL (0.39) MPLRARB
SCHEMBL15722957 0.79 FFAR4 (0.31) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9193907-B2 Liquid crystal compound having vinyloxy, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193907-B2 Liquid crystal compound having vinyloxy, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20140138582-A1 LIQUID CRYSTAL COMPOUND HAVING VINYLOXY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-22 US disclosed
US-20140138582-A1 LIQUID CRYSTAL COMPOUND HAVING VINYLOXY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-22 US disclosed