Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.80 |
| ▸ | TP53 | P04637 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | THRB | P10828 | 1/20 | 0.80 |
| ▸ | NMT1 | P30419 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | TGM2 | P21980 | 1/20 | 0.65 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.65 |
| ▸ | MMP1 | P03956 | 4/20 | 0.63 |
| ▸ | MMP2 | P08253 | 4/20 | 0.63 |
| ▸ | MMP9 | P14780 | 4/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15709188 | 0.93 | TGM2 (0.73) | SMN1; SMN2TP53MAPTTHRBNPC1 | |
| SCHEMBL15709186 | 0.93 | TGM2 (0.73) | SMN1; SMN2TP53MAPTTHRBNPC1 | |
| SCHEMBL14578749 | 0.87 | NMT1 (0.85) | SMN1; SMN2TP53MAPTTHRBNMT1 | |
| SCHEMBL890966 | 0.86 | KMT2A (0.76) | SMN1; SMN2TP53MAPTTHRBNMT1 | |
| SCHEMBL13113091 | 0.86 | TGM2 (0.65) | SMN1; SMN2TP53MAPTTHRBNPC1 | |
| SCHEMBL13174794 | 0.86 | KMT2A (0.76) | SMN1; SMN2TP53MAPTTHRBNMT1 | |
| SCHEMBL890965 | 0.86 | KMT2A (0.76) | SMN1; SMN2TP53MAPTTHRBNMT1 | |
| SCHEMBL3041662 | 0.85 | TP53 (0.65) | SMN1; SMN2TP53MAPTTHRBNMT1 | |
| SCHEMBL3041658 | 0.85 | TP53 (0.65) | SMN1; SMN2TP53MAPTTHRBNMT1 | |
| SCHEMBL15709144 | 0.85 | TGM2 (0.63) | SMN1; SMN2TP53MAPTTHRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140142333-A1 | NOVEL ANILINE DERIVATIVES AND USE THEREOF | NEOMICS Co, Ltd. (KR) | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142333-A1 | NOVEL ANILINE DERIVATIVES AND USE THEREOF | MCL1, GOT2, DDX21 | SMN1; SMN2 1227/4885TP53 9/4885MAPT 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.