Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | MMP1 | P03956 | 2/20 | 0.68 |
| ▸ | MMP2 | P08253 | 2/20 | 0.68 |
| ▸ | MMP9 | P14780 | 2/20 | 0.68 |
| ▸ | EGFR | P00533 | 1/20 | 0.68 |
| ▸ | NMT1 | P30419 | 1/20 | 0.67 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.66 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.66 |
| ▸ | TGM2 | P21980 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | TDP2 | O95551 | 1/20 | 0.64 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13174794 | 1.00 | KMT2A (0.76) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL890966 | 1.00 | KMT2A (0.76) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL15709186 | 0.93 | TGM2 (0.73) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL15709188 | 0.93 | TGM2 (0.73) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL15724554 | 0.86 | SMN1; SMN2 (0.80) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13113091 | 0.86 | TGM2 (0.65) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL25216595 | 0.85 | F3 (0.68) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11133691 | 0.85 | LPAR2 (0.88) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11137034 | 0.85 | LPAR2 (0.88) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL15709144 | 0.85 | TGM2 (0.63) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746114-B2 | Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation | UNIVERSITY OF WINDSOR (CA) | 2023-09-05 | — | — | US | disclosed |
| US-11560387-B2 | Thermally sensitive protecting groups for cysteine, and manufacture and use thereof | UNIVERSITY OF WINDSOR (CA) | 2023-01-24 | — | — | US | disclosed |
| US-20220153749-A1 | Thermally Sensitive Protecting Groups for Cysteine for Peptide Cyclization and Selective Disulfide Bond Formation | UNIVERSITY OF WINDSOR (CA) | 2022-05-19 | — | — | US | disclosed |
| US-20220024942-A1 | Thermally Sensitive Protecting Groups for Cysteine, and Manufacture and Use Thereof | UNIVERSITY OF WINDSOR | 2022-01-27 | — | — | US | disclosed |
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2019-01-15 | — | — | US | disclosed |
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2019-01-15 | — | — | US | disclosed |
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | COR THERAPEUTICS, INC. | 2018-02-08 | — | — | US | disclosed |
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | COR THERAPEUTICS, INC. | 2018-02-08 | — | — | US | disclosed |
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | COR THERAPEUTICS, INC. | 2018-02-08 | — | — | US | disclosed |
| US-9629831-B2 | Benzamides and related inhibitors of factor XA | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-6844367-B1 | Benzamides and related inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-01-18 | — | — | US | disclosed |
| US-6835739-B2 | Benzamides and related inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-12-28 | — | — | US | disclosed |
| US-20040097561-A1 | For therapy of thrombosis | MILLENNIUM PHARMACEUTICALS, INC. | 2004-05-20 | — | — | US | disclosed |
| US-20030162690-A1 | Bood anticoagulant | COR THERAPEUTICS, INC. | 2003-08-28 | — | — | US | disclosed |
| EP-1259485-A2 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR Xa | Millennium Pharmaceuticals, Inc. (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-1216228-A2 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR Xa | Millennium Pharmaceuticals, Inc. (US) | 2002-06-26 | — | — | EP | disclosed |
| US-6376515-B2 | DERIVATIVES OF A 2-((4-AMIDINYLPHENYL)-CARBONYLAMINO-1,2-PHENYLENE)-CARBONYLAMINO-) PYRIDINE; POTENT AND HIGHLY SELECTIVE ANTICOAGULANTS; BIOAVAILABILITY AND/OR SOLUBILITY; PREVENTION AND TREATMENT OF THROMBOSIS AND COAGULATION | COR THERAPEUTICS, INC. | 2002-04-23 | — | — | US | disclosed |
| US-20020002183-A1 | Derivatives of a 2-((4-amidinylphenyl)-carbonylamino-1,2-phenylene)-carbonylamino-)pyridine; potent and highly selective anticoagulants; bioavailability and/or solubility; prevention and treatment of thrombosis and coagulation | MILLENNIUM PHARMACEUTICALS, INC. | 2002-01-03 | — | — | US | disclosed |
| WO-2001064643-A2 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-09-07 | — | — | WO | disclosed |
| WO-2001019788-A2 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153749-A1 | Thermally Sensitive Protecting Groups for Cysteine for Peptide Cyclization and Selective Disulfide Bond Formation | PTMS, CTH, VIP | KMT2A 3657/4885MEN1 358/4885ALDH1A1 351/4885 |
| US-20040097561-A1 | For therapy of thrombosis | F2, F12, TFPI | KMT2A 2533/4885MEN1 1683/4885ALDH1A1 1306/4885 |
| US-20220024942-A1 | Thermally Sensitive Protecting Groups for Cysteine, and Manufacture and Use Thereof | CTH, TXN, CBS | KMT2A 3335/4885MEN1 924/4885ALDH1A1 38/4885 |
| US-11560387-B2 | Thermally sensitive protecting groups for cysteine, and manufacture and use thereof | CTH, TXN, CBS | KMT2A 3335/4885MEN1 924/4885ALDH1A1 38/4885 |
| US-11746114-B2 | Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation | PTMS, CTH, VIP | KMT2A 3657/4885MEN1 358/4885ALDH1A1 351/4885 |
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | TFPI, F12, TFPI2 | KMT2A 1317/4885MEN1 1523/4885ALDH1A1 2339/4885 |
| US-20020002183-A1 | Derivatives of a 2-((4-amidinylphenyl)-carbonylamino-1,2-phenylene)-carbonylamino-)pyridine; potent and highly selective anticoagulants; bioavailability and/or solubility; prevention and treatment of thrombosis and coagulation | F2, F12, PLAT | KMT2A 2318/4885MEN1 990/4885ALDH1A1 755/4885 |
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | TFPI, F12, TFPI2 | KMT2A 1317/4885MEN1 1523/4885ALDH1A1 2339/4885 |
| US-20030162690-A1 | Bood anticoagulant | F2, SERPINC1, HABP2 | KMT2A 2798/4885MEN1 980/4885ALDH1A1 1625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.