SCHEMBL1572565

SCHEMBL1572565

N[C@@H](Cc1ccc(O)cc1I)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.56
▸ ALOX15 P16050 3/20 0.56
▸ HSD17B10 Q99714 3/20 0.56
▸ LMNA P02545 3/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ CYP3A4 P08684 2/20 0.56
▸ MAPT P10636 2/20 0.56
▸ NFKB1 P19838 2/20 0.56
▸ BLM P54132 2/20 0.56
▸ PMP22 Q01453 2/20 0.56
▸ KMT2A Q03164 2/20 0.56
▸ NPSR1 Q6W5P4 2/20 0.56
▸ ADORA3 P0DMS8 2/20 0.56
▸ HTR2A P28223 2/20 0.56
▸ TSHR P16473 2/20 0.56
▸ HTR1A P08908 1/20 0.56
▸ HTR2C P28335 1/20 0.56
▸ SLC6A4 P31645 1/20 0.56
▸ HTR7 P34969 1/20 0.56
▸ HTR2B P41595 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1572564 1.00 KDM4E (0.56) KDM4EALOX15HSD17B10LMNAALDH1A1
SCHEMBL31189933 1.00 KDM4E (0.56) KDM4EALOX15HSD17B10LMNAALDH1A1
SCHEMBL29286183 0.86 USP2 (0.50) KDM4EALOX15HSD17B10LMNAALDH1A1
SCHEMBL29286185 0.86 USP2 (0.50) KDM4EALOX15HSD17B10LMNAALDH1A1
SCHEMBL10938099 0.85 KMT2A (0.61) KDM4EALOX15HSD17B10LMNAALDH1A1
SCHEMBL4355962 0.85 KMT2A (0.61) KDM4EALOX15HSD17B10LMNAALDH1A1
SCHEMBL836727 0.85 KMT2A (0.61) KDM4EALOX15HSD17B10LMNAALDH1A1
SCHEMBL2679928 0.84 KDM4E (0.66) KDM4EALOX15HSD17B10LMNAALDH1A1
SCHEMBL4140820 0.84 KDM4E (0.66) KDM4EALOX15HSD17B10LMNAALDH1A1
SCHEMBL569807 0.84 SLC7A5 (0.58) KDM4EALOX15HSD17B10LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 458 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747409-A2 COLLECTION, ASSESSMENT AND EARLY DETECTION OF HUMAN LUNG CANCER BIOMARKERS IN EXHALED BREATH CONDENSATES OF MOUSE ANIMAL MODELS Hackensack Meridian Health, Inc. (US) 2026-05-27 — — EP claimed
US-12345655-B1 Subsurface defect detecting device for cylindrical components and method thereof TAIYUAN UNIVERSITY OF TECHNOLOGY (CN) 2025-07-01 — — US claimed
CN-115097144-B B-type natriuretic peptide detection kit and preparation method thereof 四川新健康成生物股份有限公司 2025-05-20 — — CN claimed
CN-119868594-A Method for radiolabelling GRPR antagonist and kit thereof 诺华股份有限公司 2025-04-25 — — CN claimed
WO-2025019709-A2 COLLECTION, ASSESSMENT AND EARLY DETECTION OF HUMAN LUNG CANCER BIOMARKERS IN EXHALED BREATH CONDENSATES OF MOUSE ANIMAL MODELS HACKENSACK MERIDIAN HEALTH, INC. (US) 2025-01-23 — — WO claimed
CN-119335197-A Kit for auxiliary diagnosis of Alzheimer's disease as well as preparation method and application thereof 四川新健康成生物股份有限公司 2025-01-21 — — CN claimed
CN-119335177-A Preparation method of alkaline phosphatase labeled CTNI antibody 桂林优利特医疗电子有限公司 2025-01-21 — — CN claimed
CN-114755410-B Alkaline phosphatase-labeled antibody reagent 三诺生物传感股份有限公司 2024-12-31 — — CN claimed
US-20240410022-A1 COLLECTION, ASSESSMENT AND EARLY DETECTION OF HUMAN LUNG CANCER BIOMARKERS IN EXHALED BREATH CONDENSATES OF MOUSE ANIMAL MODELS HACKENSACK MERIDIAN HEALTH, INC. (US) 2024-12-12 — — US claimed
CN-116471435-B Voice and caption adjusting method and device, electronic equipment and storage medium 央视国际网络有限公司 2024-11-29 — — CN claimed
US-11053249-B2 Proteasome inhibiting β-lactam prodrugs useful for the treatment of cancer and neurodegenerative disorders PHILIPPE YVES-REMY SIMON (FR) 2021-07-06 — — US claimed
US-20200216455-A1 Proteasome Inhibiting Beta-Lactam Produrgs Useful for the Treatment of Cancer and Nurodegenerative Disorders VITA API (FR) 2020-07-09 — — US claimed
WO-2018115497-A1 PROTEASOME INHIBITING ß-LACTAM PRODRUGS USEFUL FOR THE TREATMENT OF CANCER AND NEURODEGENERATIVE DISORDERS VITA API (FR) 2018-06-28 — — WO claimed
EP-3339291-A1 PROTEASOME INHIBITING SS-LACTAM PRODRUGS USEFUL FOR THE TREATMENT OF CANCER AND NEURODEGENERATIVE DISORDERS VITA API (FR) 2018-06-27 — — EP claimed
CN-102319255-B Anti-radiation spriulina polysaccharide organic bio-active iodine and application thereof ZHAO BO 2013-03-27 — — CN claimed
CN-102319255-A Anti-radiation spriulina polysaccharide organic bio-active iodine and application thereof BO ZHAO 2012-01-18 — — CN claimed
US-7399619-B2 Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for structure determination THE SCRIPPS RESEARCH INSTITUTE (US) 2008-07-15 — — US claimed
US-20050272121-A1 Translation system including an orthogonal aminoacyl-transfer RNA synthetase with a specific sequence that preferentially aminoacylates an orthogonal transfer RNA with a brominated or iodinated phenylalanine or tyrosine THE SCRIPPS RESEARCH INSTITUTE (US) 2005-12-08 — — US claimed
CN-1217658-C Organic bio-iodine and its use ZHAO BO (CN) 2005-09-07 — — CN claimed
CN-1528279-A Organic bio-iodine and its use 赵 波 2004-09-15 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050272121-A1 Translation system including an orthogonal aminoacyl-transfer RNA synthetase with a specific sequence that preferentially aminoacylates an orthogonal transfer RNA with a brominated or iodinated phenylalanine or tyrosine AARS1, NSUN3, TARBP1 KDM4E 2732/4885ALOX15 4436/4885HSD17B10 2224/4885
US-11053249-B2 Proteasome inhibiting β-lactam prodrugs useful for the treatment of cancer and neurodegenerative disorders PSMB5, PSMB1, PSMB11 KDM4E 1063/4885ALOX15 2434/4885HSD17B10 1893/4885
US-20200216455-A1 Proteasome Inhibiting Beta-Lactam Produrgs Useful for the Treatment of Cancer and Nurodegenerative Disorders PSMB5, PSMB1, PSMB11 KDM4E 1964/4885ALOX15 2878/4885HSD17B10 1810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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