Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.61 |
| ▸ | PCNA | P12004 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | THRA | P10827 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938099 | 1.00 | KMT2A (0.61) | KMT2AMEN1PPARGBLMNR1I2 | |
| SCHEMBL4355962 | 1.00 | KMT2A (0.61) | KMT2AMEN1PPARGBLMNR1I2 | |
| SCHEMBL11198572 | 0.92 | KMT2A (0.55) | KMT2AMEN1PPARGBLMNR1I2 | |
| SCHEMBL188397 | 0.87 | PCNA (0.66) | KMT2AMEN1PPARGBLMNR1I2 | |
| SCHEMBL30693721 | 0.87 | PCNA (0.66) | KMT2AMEN1PPARGBLMNR1I2 | |
| Hydrochloric Acid SCHEMBL10531318 | 0.86 | MEN1 (0.48) | KMT2AMEN1PPARGBLMNR1I2 | |
| SCHEMBL31189933 | 0.85 | KDM4E (0.56) | KMT2AMEN1PPARGBLMNR1I2 | |
| SCHEMBL1572564 | 0.85 | KDM4E (0.56) | KMT2AMEN1PPARGBLMNR1I2 | |
| SCHEMBL1572565 | 0.85 | KDM4E (0.56) | KMT2AMEN1PPARGBLMNR1I2 | |
| SCHEMBL230513 | 0.85 | KMT2A (0.52) | KMT2AMEN1PPARGBLMNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4684002-A2 | THYROCYTES AND USES THEREOF | Lifenet Health (US) | 2026-01-28 | — | — | EP | claimed |
| US-20250345488-A1 | CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2025-11-13 | — | — | US | claimed |
| CN-120121693-A | Identification of thyroid hormones using reactive heterogeneous nanopores | 南京大学 | 2025-06-10 | — | — | CN | claimed |
| WO-2024197069-A2 | THYROCYTES AND USES THEREOF | LIFENET HEALTH (US) | 2024-09-26 | — | — | WO | claimed |
| CN-116699150-A | Biosensing analysis method for detecting thyroid hormone binding activity in water sample | 清华大学 | 2023-09-05 | — | — | CN | claimed |
| US-9890116-B2 | Process for the preparation of a sulfated derivative of 3,5-diiodo-O-[3-iodophenyl]-L-tyrosine | BRACCO IMAGING S.P.A. (IT) | 2018-02-13 | — | — | US | claimed |
| EP-2694471-B1 | PROCESS FOR THE PREPARATION OF A SULFATED DERIVATIVE OF 3,5-DIIODO-O-[3-IODOPHENYL]-L-TYROSINE | BRACCO IMAGING SPA (IT) | 2017-08-02 | — | — | EP | claimed |
| US-9201079-B2 | Methods for quantifying vitamin D metabolites by mass spectrometry | GEORGETOWN UNIVERSITY (US) | 2015-12-01 | — | — | US | claimed |
| US-20150037813-A1 | ANTIBODY AGAINST AFFINITY COMPLEX | FUJIREBIO INC. (JP) | 2015-02-05 | — | — | US | claimed |
| US-20140221477-A1 | Process For The Preparation Of A Sulfated Derivative Of 3,5-Diiodo-O-[3-Iodophenyl]-L-Tyrosine | BRACCO IMAGING S.P.A. (IT) | 2014-08-07 | — | — | US | claimed |
| WO-2001035902-A9 | STABILIZED THYROXINE COMPOUNDS | LOTUS BIOCHEMICAL CORP (US) | 2001-11-29 | — | — | WO | claimed |
| WO-2001035902-A2 | STABILIZED THYROXINE COMPOUNDS | LOTUS BIOCHEMICAL CORPORATION (US) | 2001-05-25 | — | — | WO | claimed |
| WO-1996040048-A9 | NOVEL USES FOR THYROID HORMONES OR THYROID HORMONE-LIKE COMPOUNDS | — | 1997-03-27 | — | — | WO | claimed |
| EP-0357725-B1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF LUNG OBSTRUCTIONS | SMITH, Ulf Per Gustav (SE) | 1992-04-15 | — | — | EP | claimed |
| EP-0073865-B1 | DERIVATIVES OF IODOTHYRONINE COMPOUNDS AND THEIR USE IN AN ASSAY FOR THE FREE IODOTHYRONINE COMPOUNDS | AMERSHAM INTERNATIONAL plc (GB) | 1986-01-29 | — | — | EP | claimed |
| EP-0093653-B1 | PROCESS FOR THE PREPARATION OF IODO-THYRONINES AND IODO-THYROACETIC ACIDS BY ELECTROCHEMICAL REDUCTION AT A CONTROLLED POTENTIAL | SPIRAL Société à responsabilité limitée dite : (FR) | 1985-07-10 | — | — | EP | claimed |
| US-4490221-A | Process for preparing iodothyronines and iodothyroacetic acids by electrochemical reduction at controlled potential | SPIRAL SOCIETE A RESPONSABILITE LIMITEE DITE (FR) | 1984-12-25 | — | — | US | claimed |
| US-4426453-A | Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds | AMERSHAM INTERNATIONAL LIMITED (GB) | 1984-01-17 | — | — | US | claimed |
| EP-0093653-A1 | Process for the preparation of iodo-thyronines and iodo-thyroacetic acids by electrochemical reduction at a controlled potential | SPIRAL Société à responsabilité limitée dite : (FR) | 1983-11-09 | — | — | EP | claimed |
| EP-0073865-A1 | Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds | AMERSHAM INTERNATIONAL plc (GB) | 1983-03-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150037813-A1 | ANTIBODY AGAINST AFFINITY COMPLEX | FCGR3B, FCGR2A, FCGR1A | KMT2A 3494/4885MEN1 2947/4885PPARG 4393/4885 |
| US-20140221477-A1 | Process For The Preparation Of A Sulfated Derivative Of 3,5-Diiodo-O-[3-Iodophenyl]-L-Tyrosine | TH, TYRO3, TYR | KMT2A 2227/4885MEN1 3614/4885PPARG 3633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.