Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932584 | 0.79 | MAOA (0.39) | — | |
| SCHEMBL27670730 | 0.77 | ATM (0.36) | HTR2B | |
| SCHEMBL27529161 | 0.75 | HTR2B (0.33) | HTR2BTMEM97SIGMAR1HTR1AHTR7 | |
| SCHEMBL1133294 | 0.70 | HTR1A (0.35) | HTR2BTMEM97SIGMAR1HTR1A | |
| SCHEMBL17929070 | 0.69 | KCNE1 (0.43) | HTR2BABCB1 | |
| SCHEMBL15254619 | 0.69 | KCNE1 (0.43) | HTR2BABCB1 | |
| SCHEMBL29172253 | 0.69 | HTR1A (0.37) | HTR2BTMEM97SIGMAR1HTR1A | |
| SCHEMBL29172254 | 0.69 | HTR1A (0.37) | HTR2BTMEM97SIGMAR1HTR1A | |
| SCHEMBL29653988 | 0.69 | HTR1A (0.37) | HTR2BTMEM97SIGMAR1HTR1A | |
| SCHEMBL26759117 | 0.69 | HTR1A (0.37) | HTR2BTMEM97SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014075874-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-22 | — | — | WO | disclosed |