SCHEMBL157282

SCHEMBL157282

COc1ccc(CNO)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
PKM P14618 1/20 0.62
CHRM2 P08172 1/20 0.55
IDO1 P14902 2/20 0.52
HTT P42858 3/20 0.52
NPC1 O15118 2/20 0.52
MEN1 O00255 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
RAB9A P51151 1/20 0.52
KMT2A Q03164 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
LMNA P02545 2/20 0.50
THRB P10828 1/20 0.50
F2RL1 P55085 1/20 0.50
HDAC3 O15379 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL15660534 0.98 ALDH1A1 (0.60) ALDH1A1PKMCHRM2IDO1HTT
SCHEMBL25191115 0.90 MAPT (0.63) ALDH1A1PKMCHRM2HTTNPC1
SCHEMBL8545698 0.85 ALDH1A1 (0.49) ALDH1A1PKMHTTMEN1KMT2A
SCHEMBL3388335 0.84 CHRM2 (0.58) ALDH1A1PKMCHRM2HTTMEN1
SCHEMBL121529 0.81 CHRM2 (0.70) ALDH1A1PKMCHRM2IDO1HTT
SCHEMBL7346729 0.81 ALDH1A1 (0.61) ALDH1A1PKMCHRM2IDO1HTT
Hydrochloric Acid SCHEMBL7034100 0.79 ALDH1A1 (0.59) ALDH1A1PKMCHRM2IDO1HTT
Hydrochloric Acid SCHEMBL2147064 0.79 CHRM2 (0.68) ALDH1A1PKMCHRM2HTTGAA
SCHEMBL8278372 0.79 IDO1 (0.60) ALDH1A1PKMCHRM2IDO1HTT
Hydrochloric Acid SCHEMBL9479560 0.79 CHRM2 (0.68) ALDH1A1PKMCHRM2HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121850924-A Curing stabilizer, sealant based on curing stabilizer and preparation method of sealant 广州白云科技股份有限公司 2026-04-14 CN disclosed
EP-4703355-A1 FLUORINE-CONTAINING ISOXAZOLONE COMPOUND AND PRODUCTION METHOD FOR SAME Unimatec Co., Ltd. (JP) 2026-03-04 EP disclosed
WO-2024225214-A1 FLUORINE-CONTAINING ISOXAZOLONE COMPOUND AND PRODUCTION METHOD FOR SAME ユニマテック株式会社 2024-10-31 WO disclosed
US-20240294470-A1 FRAGRANCE COMPOUNDS GIVAUDAN SA (CH) 2024-09-05 US disclosed
EP-4355728-A1 FRAGRANCE COMPOUNDS Givaudan SA (CH) 2024-04-24 EP disclosed
CN-117500783-A Perfume compounds 奇华顿股份有限公司 2024-02-02 CN disclosed
WO-2022261956-A1 FRAGRANCE COMPOUNDS GIVAUDAN SA (CH) 2022-12-22 WO disclosed
WO-2022263605-A1 FRAGRANCE COMPOUNDS GIVAUDAN SA (CH) 2022-12-22 WO disclosed
WO-2022068933-A1 COMPOUNDS AND METHODS OF TREATING DISEASES CULLGEN (SHANGHAI) , INC. (CN) 2022-04-07 WO disclosed
CN-107108657-B Tosylate salt of compound 伊莱利利公司 2021-10-08 CN disclosed
EP-0740652-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-11-06 EP disclosed
WO-1995019956-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1995-07-27 WO disclosed
EP-0641327-A1 NOVEL ALPHA-MANNOSIDASE INHIBITORS MERRELL PHARMACEUTICALS INC. (US) 1995-03-08 EP disclosed
EP-0641327-A4 NOVEL ALPHA-MANNOSIDASE INHIBITORS. MERRELL DOW PHARMA (US) 1994-06-01 EP disclosed
US-5262425-A Immunostimulants, chemoprotective and radioprotective agents, antimetastatic agents MERRELL DOW PHARMACEUTICALS INC. (US) 1993-11-16 US disclosed
WO-1993005781-A1 NOVEL ALPHA-MANNOSIDASE INHIBITORS MERRELL DOW PHARMACEUTICALS INC. (US) 1993-04-01 WO disclosed
EP-0223588-B1 PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-06-12 EP disclosed
EP-0310061-A1 5-Mono or Disubstituted-3-(phenyl or 2-naphthalenyl)-3-[(1H-imidazol-1-ylmethyl) or (1H-1,2,4-triazol-1-ylmethyl)]-2-(methyl or benzyl)isoxazolidines FISONS CORPORATION (US) 1989-04-05 EP disclosed
US-4749793-A 5-substituted-3-phenyl-3-[1H-imidazol-1-ylmethyl) or (1H-1,2,4-triazol-1-ylmethyl]-2-benzylisoxazolidines (ir 3011) PENNWALT CORPORATION (US) 1988-06-07 US disclosed
EP-0223588-A1 Process for the preparation of beta-lactam compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240294470-A1 FRAGRANCE COMPOUNDS FASN, FAAH2, FADS2 ALDH1A1 27/4885PKM 310/4885CHRM2 4042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.