Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549943 | 0.86 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2KDM4EHTTST14 | |
| SCHEMBL157282 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HTTPKMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15660534 | 0.83 | ALDH1A1 (0.60) | ALDH1A1HTTPKMMEN1KMT2A | |
| SCHEMBL8544291 | 0.82 | ST14 (0.46) | ST14LTA4H | |
| SCHEMBL8547795 | 0.82 | CARM1 (0.52) | ALDH1A1SMN1; SMN2KDM4EHTTST14 | |
| SCHEMBL8545423 | 0.81 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2KDM4EHTTST14 | |
| SCHEMBL8545697 | 0.81 | ST14 (0.42) | ALDH1A1SMN1; SMN2KDM4EHTTST14 | |
| SCHEMBL27336667 | 0.79 | THRB (0.45) | ALDH1A1SMN1; SMN2PKMMEN1KMT2A | |
| SCHEMBL2218696 | 0.77 | THRB (0.64) | ALDH1A1SMN1; SMN2KDM4EHTTMEN1 | |
| SCHEMBL8544608 | 0.77 | ST14 (0.58) | ALDH1A1ST14KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |