Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA4 | P22748 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KDM5C | P41229 | 3/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | EPOR | P19235 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896372 | 1.00 | CA12 (0.46) | CA12CA1CA2CA4CA9 | |
| SCHEMBL13581469 | 0.98 | PHF8 (0.46) | CA12CA1CA2CA4CA9 | |
| SCHEMBL19643616 | 0.96 | CA12 (0.44) | CA12CA1CA2CA4CA9 | |
| SCHEMBL16781066 | 0.92 | CA12 (0.42) | CA12CA1CA2CA4CA9 | |
| SCHEMBL16780867 | 0.92 | CA12 (0.42) | CA12CA1CA2CA4CA9 | |
| SCHEMBL16353585 | 0.92 | CA12 (0.42) | CA12CA1CA2CA4CA9 | |
| SCHEMBL16781067 | 0.92 | CA12 (0.42) | CA12CA1CA2CA4CA9 | |
| SCHEMBL23157585 | 0.91 | CA2 (0.44) | CA12CA1CA2CA4CA9 | |
| SCHEMBL158484 | 0.91 | CA2 (0.44) | CA12CA1CA2CA4CA9 | |
| SCHEMBL23157519 | 0.91 | CA2 (0.44) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266652-B2 | Cross-linked poly-E-lysine non-particulate support | SPHERITECH LTD. (GB) | 2019-04-23 | — | — | US | disclosed |
| US-20190023844-A1 | Cross-Linked Poly-E-Lysine Non-Particulate Support | SPHERITECH LTD. (GB) | 2019-01-24 | — | — | US | disclosed |
| US-9938378-B2 | Cross-linked poly-E-lysine non-particulate support | SPHERITECH LTD (GB) | 2018-04-10 | — | — | US | disclosed |
| US-20140154737-A1 | CROSS-LINKED POLY-E-LYSINE PARTICLES | SPHERITECH LTD (GB) | 2014-06-05 | — | — | US | disclosed |
| US-20140142198-A1 | CROSS-LINKED POLY-E-LYSINE NON-PARTICULATE SUPPORT | SPHERITECH LTD (GB) | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023844-A1 | Cross-Linked Poly-E-Lysine Non-Particulate Support | PLOD3, PCNA, POLK | CA12 2759/4885CA1 3384/4885CA2 3378/4885 |
| US-10266652-B2 | Cross-linked poly-E-lysine non-particulate support | PLOD3, PCNA, POLK | CA12 2853/4885CA1 3454/4885CA2 3429/4885 |
| US-20140142198-A1 | CROSS-LINKED POLY-E-LYSINE NON-PARTICULATE SUPPORT | PLOD3, PCNA, POLK | CA12 2759/4885CA1 3384/4885CA2 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.