SCHEMBL157299

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14092491	0.84	L3MBTL1 (0.49)	RAB9AMAPTNPC1PTGDR2MEN1
	SCHEMBL95063	0.83	RAB9A (0.56)	RAB9AMAPTNPC1PTGDR2MEN1
	SCHEMBL592715	0.81	POLB (0.66)	RAB9AMAPTNPC1PTGDR2MEN1
	SCHEMBL7590812	0.80	RAB9A (0.53)	RAB9AMAPTNPC1PTGDR2MEN1
	SCHEMBL7590807	0.80	RAB9A (0.53)	RAB9AMAPTNPC1PTGDR2MEN1
	SCHEMBL5002002	0.79	HTT (0.58)	RAB9AMAPTNPC1MEN1KMT2A
	SCHEMBL4726901	0.79	SMN1; SMN2 (0.45)	RAB9AMAPTNPC1PTGDR2MEN1
	SCHEMBL4993936	0.78	SMN1; SMN2 (0.44)	RAB9AMAPTNPC1PTGDR2ALDH1A1
	SCHEMBL5001623	0.78	ALDH1A1 (0.54)	RAB9AMAPTNPC1PTGDR2MEN1
	SCHEMBL4998991	0.78	RAB9A (0.43)	RAB9AMAPTNPC1PTGDR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.